Your search matched a total of 41 documents. Results 1 - 10.
Homo sapiens
Gene: ... that this transcription factor is involved in human angiogenesis. Anatomical context of EPAS1 EPAS1 was detected in all...Disease relevance of EPAS1 Exposure of cultured A549 cells to hypoxia increased EPAS1 mRNA and protein levels. We showed that EPAS1, but not HIF- 1alpha, is abundantly expressed in human lung... / Synonyms: EPAS-1
Rattus norvegicus
Gene: ... Disease relevance of Epas1 EPAS1 trans- activation during hypoxia requires p42/ p44 MAPK. Here we... transduced with adenovirus expressing EPAS1. High impact information on Epas1 Interestingly, NGF effect... no effect on EPAS1 phosphorylation during hypoxia, suggesting that MAPK targets other proteins... / Synonyms: EPAS-1
Mus musculus
Gene: ... Disease relevance of Epas1 Cre- mediated removal of the inserted gene recovered normal HLF... sandwiched between two loxP sequences into exon 1 of the HLF gene. EPAS1- null as well as heterozygous mice... lacking wild- type HIF- 2alpha, encoded by the EPAS1 gene, exhibit pancytopenia. High impact information... / Synonyms: EPAS-1
Gallus gallus
Gene: ... High impact information on EPAS1 In contrast, sequence homology between the chick HIF- 1alpha and endothelial PAS protein 1( EPAS1 ), another member of the bHLH- PAS proteins, was only low( 49 %)....
Bos taurus
Gene: ... Disease relevance of EPAS1 Since VEGF plays a crucial role in angiogenesis, the ability of dominant- negative EPAS1 to inhibit VEGF promoter activity raises the possibility of a novel approach to inhibiting pathological angiogenesis. High impact information on EPAS1 In this report, we show that EPAS1 increased VEGF...
MeSH term: ... of HIF- 1 alpha transactivation domains with coactivators is induced by hypoxia. We hypothesize that EPAS1 expressed in the OZ senses hypoxia during mid- gestational development and translates this signal..., is synthesized in the kidney and liver in response to hypoxia. These observations raise the possibility that EPAS...
MeSH term: ... system, EPAS1- deficient mice display pronounced bradycardia. Thioridazine( Mellaril) hydrochloride..., whereas sinus bradycardia was associated with LQT1. All HR effects were probably mediated by CRF( 1...
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Steven Johnsen and Donald R. Forsdyke and Kehinde Ross and Andrew Perry and Jonathan Eisen and A. Shimabukuro-Vornhagen and Giuseppe Rotondo and Gordon Laurie and Berkley Lynch and Kung-Hao Liang and Matthias Gstaiger and Thomas Pfeiffer and Marta Ramirez and Grant MacGregor and Jingyu Li and Fedik Rahimov and M El Gizouli and Marta Ramirez Gaite and Oswaldo Ribeiro-filho and Ralf Weigel and Bjoern Hamberger and Alexander Kanitz and Andreas Zankl and Chunming Ding and Maruf Yunus and Jonathan S. Berg and Michael Cariaso and Zakir Thomas and Monique Timberlake-Brady and LC Dore and Nan Shen and R. Eric Collins and Kuang-Mao Chiang and Brendan McMahon and John Chew and Wen-Ming Yang and Robert Hoffmann and J.B. Stewart and Manuela Cucerea and Ignacio García and William James and Thomas Kelder and Gregory Melahn and YINGDE ZHU and Andres Muro and Gabriel Santpere and Jeff Freilich and Junbin Qian and Steffen Poulsen and Eric Villard and Rafael Sidi and Grant Cramer and Chris Sander and Alexandre Chigaev and Florian Uhle and Carl Fulp and Andrew Brown and Xiaozhu Zhou and Corina Dutu and Hilary Spencer and david germano and Abbas Dehghan and Eung-ju PARK and Chris Sander and Albert Vilella and Miao Tian and Anjali Bheda and Michael Nevels and Jun Liu and D Delano and Chitose Taya and Soomi Cheong and David Kavanagh and Maha Karnoub and Hilmar Lapp and Christian Pallasch and Daniel Mietchen and Biju Balakrishnan and Keith Ashman and Juan Carlos Sobrino and Anshu Bhardwaj and Grzegorz Wickiel and Matthew Day and Anthony Sebastian and Vedran Katavic and Liang Long and Barry Wanner and Sarah Snelling and Fernando Montanes and Omobosede Fashedemi and Gustavo Cervantes and Manoj Kumar and Edward D Great and Paul Paukstelis and Roy Soetikno and Ana I Caño-Delgado and Minsoo Choi and Lei Wang and Brenda Riley and A Michelle Moon and Jon Moulton and Mahmoud Elshahawy and Meagan Gillespie and Banundari Rachmawati and Qian Han and Eric Danner and Xavier Fouillet and Madhusudhan Acharya and Brian Young and Chandra Sekhar Mukhopadhyay and shrawan bhattacharjee and Marieke van der Linden and cj hoban and Sandi Pniauskas and jackie gao and Metin Bilgin and Gillian L. Dalgliesh and Karl Wotton and Iveta Herichova and Yuji Morita and Marta Hernandez and Gregor Krings and Marco Briones and Tim D. Smith and Yiumo Michael Chan and Zhenyu Guo and Barry Barclay and Hong Wang and tarali chowdhury and Tilman Brummer and Nuno Faria and Tamir Ben David and Myles Axton and Yannick Fonseca and Francis Castets and Modesto Redrejo-Rodríguez and Bruce Herron and Toshio Fujita and Elena Puccetti and Zhang Zhang and John Osborne and Illes J Farkas and Fernando Andres and Phyllis Pugh and Jonathan Court and Tim Vickers and Nir Friedman and Holger Dick and Ya-Chen Liang and Jonathan Froehlich and Haitham Sobhy and David Abraham and Stephane Krief and Yaroslav Nikolaev and Qiping Feng and d gupta and R Thapar and Susan Wee and Michael Rehman and SOUMITRA GHOSH and Mohamed Eweida and Cedric Uytingco and Nie hongchuan and David Steenblock and Mark A. Kukucka and Zoli Fekete and Sergei Kozlov and Javier Jara and Osama Naguib and Felix Benninger and jean-marc lo-guidice and VASUDEVA BHAT and Anne O. Summers and Bjoern Titz and Anna Levine and Klas Udekwu and Robert Hoffmann
