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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Your search matched a total of 204 documents. Results 1 - 10.

Homo sapiens
Gene: ... Disease relevance of GATA1 Together, these findings indicate that loss of wildtype GATA1... and thrombocytopenia due to an inherited mutation in GATA1. Acquired mutations in megakaryocyte transcription factor GATA1 have recently been reported in Down syndrome( DS ), transient myeloproliferative disorder( TMD... / Synonyms: GATA-1
Mus musculus
Gene: ... Disease relevance of Gata1 In the absence of the hematopoietic transcription factor GATA- 1, mice... abnormalities. Surprisingly, TPO treatment of GATA- 1( low) mice restored the GATA- 1 content in Mks and halted... megakaryoblastic leukemia harbor mutations in GATA1 that lead to the exclusive expression of a shorter isoform... / Synonyms: GATA-1; Gata-1
Danio rerio
Gene: ... High impact information on gata1 A nonsense mutation in zebrafish gata1 causes the bloodless phenotype in vlad tepes. These results thus provide the first in vivo evidence that the ability of Gata1 to self- associate critically contributes to the autoregulation of the gata1 gene. Of the tested mutations... / Synonyms: gata1
Rattus norvegicus
Gene: ... Disease relevance of Gata1 Rat GATA- 1 expressed as a GST- fusion protein in E. coli bound... and if so, how these factors are modulated during this process. Among 15 WT1- expressing leukemias, GATA- 1... expressed in 13 cases( p< 0. 05). High impact information on Gata1 Mutations introduced into consensus... / Synonyms: GATA-1
Arabidopsis thaliana
Gene: ... finger DNA- binding domain of GATA1 and steroid hormone receptors, but has a longer putative loop than... that GATA- 1 could also bind specifically to a cis- acting element in the promoter of the GAPA gene, which... Gel mobility shift assays showed that GATA- 1, but not GATA- 20, binds specifically to the two GATA...
Homo sapiens
Gene: ... finger of GATA- 1 affecting DNA binding rather than FOG- 1 interaction. Alterations of the FOG- 1 face... occupancy by GATA- 1 at sites bound by GATA- 2. However, at DNase I- hypersensitive site( HS) 3 of the beta- globin locus control region, GATA- 1- induced histone acetylation was FOG- 1- independent. In contrast... / Synonyms: Friend of GATA 1
Gallus gallus
Gene: ... Disease relevance of LOC396450 Each of these GATA- 1 sites had an enhancer activity when inserted..., and erythroblasts, showing that the effects of GATA- 1 are not limited to Myb- Ets- transformed myeloblasts. GATA- 1... contain a specialized TATA box at- 30( GATA) through which the erythroid- restricted protein cGATA- 1...
Xenopus laevis
Gene: Synonyms: GATA-1; gata1; gata1a-A
Xenopus laevis
Gene: Synonyms: gata-1; gata1b-A; xGATA-1


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