Your search matched a total of 72 documents. Results 1 - 10.
Mus musculus
Gene: ... , Gfi1 mutant mice lose all cochlear hair cells just prior to and soon after birth through apoptosis. We...Disease relevance of Gfi1 Heightened expression of Gfi1 distinguishes MZL from other lymphoma types. Inflammatory reactions and severe neutropenia in mice lacking the transcriptional repressor Gfi1. Gfi1... / Synonyms: Gfi-1; Zinc finger protein Gfi-1
Caenorhabditis elegans
Gene: ... High impact information on gfi- 1 The C. elegans gene pag- 3 is homologous to the zinc finger proto- oncogene gfi- 1....
Homo sapiens
Gene: ... Disease relevance of GFI1 Mutations in proto- oncogene GFI1 cause human neutropenia and target ELA2. Electrophoretic mobility assays with nuclear extracts from prostate cancer cell lines established binding of GFI1... that GFI1, as with ASH1, is expressed in neuroendocrine lung cancer cell lines and that GFI1 in lung cancer... / Synonyms: GFI-1; GFI1A; Zinc finger protein Gfi-1
Rattus norvegicus
Gene: ... Disease relevance of Gfi1 Gfi- 1 is a zinc finger transcriptional repressor originally recognized for its role in T cell differentiation and lymphomas. Recent experiments reveal that gene- targeted Gfi- 1- deficient mice are neutropenic and that Gfi- 1 mutations cause human neutropenia. Expression of Gfi- 1... / Synonyms: Gfi-1; Zinc finger protein Gfi-1
Mus musculus
Gene: ... High impact information on Gfi1b Gfi1b is a 37 kDa nuclear protein with six C2H2 zinc- finger domains that can silence transcription upon binding to specific target gene promoters. Gfi1b alters.... Elevated levels of Gfi1b correlated with increased histone H3 lysine 9 dimethylation at sites neighboring... / Synonyms: Gfi-1B; Zinc finger protein Gfi-1b
Homo sapiens
Gene: ... High impact information on GFI1B The human homologue( GFI1B) of the chicken GFI gene maps... and megakaryocytic lineages. Silencing GFI1B by transfection with small interfering RNA( siRNA) markedly reduced the proliferation rate in the leukaemic cell lines HEL, K562 and NB4( P< 0. 01). GFI1B expression was increased... / Synonyms: Zinc finger protein Gfi-1b
MeSH term: ... of thymocytes and bone marrow B lineage progenitors to 20% of normal levels. We have generated Gfi1- deficient mice( Gfi1 -/-) and show that these animals are severely neutropenic and accumulate immature monocytic...
Danio rerio
Gene: Synonyms: gfi1; gfi1.2; gfi1b
MeSH term: ... of Monocytes We conclude that Gfi1 influences the differentiation of myeloid precursors into granulocytes...
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Steven Johnsen and Donald R. Forsdyke and Kehinde Ross and Andrew Perry and Jonathan Eisen and A. Shimabukuro-Vornhagen and Giuseppe Rotondo and Gordon Laurie and Berkley Lynch and Kung-Hao Liang and Matthias Gstaiger and Thomas Pfeiffer and Marta Ramirez and Grant MacGregor and Jingyu Li and Fedik Rahimov and M El Gizouli and Marta Ramirez Gaite and Oswaldo Ribeiro-filho and Ralf Weigel and Bjoern Hamberger and Alexander Kanitz and Andreas Zankl and Chunming Ding and Maruf Yunus and Jonathan S. Berg and Michael Cariaso and Zakir Thomas and Monique Timberlake-Brady and LC Dore and Nan Shen and R. Eric Collins and Kuang-Mao Chiang and Brendan McMahon and John Chew and Wen-Ming Yang and Robert Hoffmann and J.B. Stewart and Manuela Cucerea and Ignacio García and William James and Thomas Kelder and Gregory Melahn and YINGDE ZHU and Andres Muro and Gabriel Santpere and Jeff Freilich and Junbin Qian and Steffen Poulsen and Eric Villard and Rafael Sidi and Grant Cramer and Chris Sander and Alexandre Chigaev and Florian Uhle and Carl Fulp and Andrew Brown and Xiaozhu Zhou and Corina Dutu and Hilary Spencer and david germano and Abbas Dehghan and Eung-ju PARK and Chris Sander and Albert Vilella and Miao Tian and Anjali Bheda and Michael Nevels and Jun Liu and D Delano and Chitose Taya and Soomi Cheong and David Kavanagh and Maha Karnoub and Hilmar Lapp and Christian Pallasch and Daniel Mietchen and Biju Balakrishnan and Keith Ashman and Juan Carlos Sobrino and Anshu Bhardwaj and Grzegorz Wickiel and Matthew Day and Anthony Sebastian and Vedran Katavic and Liang Long and Barry Wanner and Sarah Snelling and Fernando Montanes and Omobosede Fashedemi and Gustavo Cervantes and Manoj Kumar and Edward D Great and Paul Paukstelis and Roy Soetikno and Ana I Caño-Delgado and Minsoo Choi and Lei Wang and Brenda Riley and A Michelle Moon and Jon Moulton and Mahmoud Elshahawy and Meagan Gillespie and Banundari Rachmawati and Qian Han and Eric Danner and Xavier Fouillet and Madhusudhan Acharya and Brian Young and Chandra Sekhar Mukhopadhyay and shrawan bhattacharjee and Marieke van der Linden and cj hoban and Sandi Pniauskas and jackie gao and Metin Bilgin and Gillian L. Dalgliesh and Karl Wotton and Iveta Herichova and Yuji Morita and Marta Hernandez and Gregor Krings and Marco Briones and Tim D. Smith and Yiumo Michael Chan and Zhenyu Guo and Barry Barclay and Hong Wang and tarali chowdhury and Tilman Brummer and Nuno Faria and Tamir Ben David and Myles Axton and Yannick Fonseca and Francis Castets and Modesto Redrejo-Rodríguez and Bruce Herron and Toshio Fujita and Elena Puccetti and Zhang Zhang and John Osborne and Illes J Farkas and Fernando Andres and Phyllis Pugh and Jonathan Court and Tim Vickers and Nir Friedman and Holger Dick and Ya-Chen Liang and Jonathan Froehlich and Haitham Sobhy and David Abraham and Stephane Krief and Yaroslav Nikolaev and Qiping Feng and d gupta and R Thapar and Susan Wee and Michael Rehman and SOUMITRA GHOSH and Mohamed Eweida and Cedric Uytingco and Nie hongchuan and David Steenblock and Mark A. Kukucka and Zoli Fekete and Sergei Kozlov and Javier Jara and Osama Naguib and Felix Benninger and jean-marc lo-guidice and VASUDEVA BHAT and Anne O. Summers and Bjoern Titz and Anna Levine and Klas Udekwu and Robert Hoffmann
