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Gene Review

Gfi1  -  growth factor independent 1 transcription...

Rattus norvegicus

Synonyms: Gfi-1, Growth factor independent protein 1, Zinc finger protein Gfi-1
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Disease relevance of Gfi1


High impact information on Gfi1


Biological context of Gfi1

  • In mitogen-stimulated splenocytes, Gfi-1 expression begins to rise at 12 h after stimulation and reaches very high levels after 50 h, suggesting that it may be functionally involved in events occurring after the interaction of IL-2 with its receptor, perhaps during the transition from the G1 to the S phase of the cell cycle [2].
  • Addition of PRL to such stationary cells led to induction of Gfi-1 gene expression within a few hr with a maximum in late G1 [3].
  • In the present study, a novel, 14p22 zinc finger protein-encoding gene, Gfi-1, has been examined for a role in Nb2 cell proliferation [3].

Other interactions of Gfi1


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