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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Your search matched a total of 399 documents. Results 1 - 10.

Mus musculus
Gene: ... Disease relevance of Hdac1 We investigated the role of a histone deacetylase( HDAC )- dependent... the HDAC1 gene in other mouse strains such as C57B16, C3H/ An and C- RY lacks the retrovirus. In the genome of 129SV mice the largest intervening sequence of the HDAC1 gene, intron 3, harbors a complete copy... / Synonyms: Hdac1-ps
Homo sapiens
Gene: ... Disease relevance of HDAC1 ETO, fusion partner in t( 8; 21) acute myeloid leukemia, represses transcription by interaction with the human N- CoR/ mSin3/ HDAC1 complex. Conversely, exposure of cells... in the displacement of HDAC1 from nuc 1, in association with increased acetylation of histone H4. In this study, we...
Rattus norvegicus
Gene: ... Disease relevance of Hdac1 Histone deacetylase( HDAC) inhibitors are emerging as a new class... to play a central role in chronic liver diseases. Psychiatry related information on Hdac1 Valproic acid...). High impact information on Hdac1 The action of valproic acid has been linked to both inositol depletion... / Synonyms: Hdac1
Danio rerio
Gene: ... High impact information on hdac1 These data suggest that Hdac1 antagonizes these pathways... identify hdac1 as a novel, essential component of the mechanism that allocates neural progenitors... specification in the zebrafish CNS. The effect of HDAC1 on cell cycle exit is cell- autonomous, and loss of HDAC... / Synonyms: hdac-1
Gallus gallus
Gene: ... Disease relevance of HDAC1 We conclude that quinidine is a breast tumor cell differentiating agent that causes the loss of HDAC1 via a proteasomal sensitive mechanism. Reactivation of repressed genes in APL... information on HDAC1 Treatment with inhibitors of histone deacetylase or DNA methylation reverses...
Bos taurus
Gene: ... High impact information on HDAC1 Trichostatin A( TSA; 0- 5 microM ), a histone deacetylase inhibitor, was used to increase histone acetylation and 5- aza- 2 '- deoxycytidine( 5- aza- dC; 0- 5 microM ), a DNA methyl- transferase inhibitor, was used to decrease methylation of chromatin in donor cells...
Drosophila melanogaster
Gene: ... to recruitment of the histone deacetylase dHDAC1 to the promoter of the gene encoding the antibacterial protein... PRE in vivo, suggesting that they act directly at the PRE. We show that Drosophila Hdac1, an Rpd3... by Gal4- dHDAC1 was blocked by the deacetylase inhibitor, FR901228, and thus, deacetylase activity... / Synonyms: DmHDAC1; HDAC-1; HDAC1
Rattus norvegicus
Xenopus (Silurana) tropicalis
Gene: Synonyms: hdac1-b
Xenopus laevis
Gene: Synonyms: hdac1; hdac1b


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