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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Your search matched a total of 141 documents. Results 1 - 10.

Homo sapiens
Gene: ... Disease relevance of IRF1 Human serum from patients with septic shock activates transcription factors STAT1, IRF1, and NF- kappaB and induces apoptosis in human cardiac myocytes. Alterations in IRF1/ IRF2 expression in acute myelogenous leukemia. The ATRA- induced expression of IRF- 1, an activator... / Synonyms: IRF-1
Mus musculus
Gene: ... Disease relevance of Irf1 In contrast, mice deficient for IRF1 were not able to produce nitric... and that antitumor actions of IRF- 1/ ICSBP can be exploited therapeutically to circumvent adverse clinical effects... induce pulmonary inflammation in vivo and that IRF- 1 is involved in some of the cytokine responses... / Synonyms: IRF-1; Irf-1
Xenopus (Silurana) tropicalis
Gene: ... High impact information on irf1 An interferon regulatory factor- like binding element restricts Xmyf- 5 expression in the posterior somites during Xenopus myogenesis.... / Synonyms: irf-1
Rattus norvegicus
Gene: ... Disease relevance of Irf1 In C57BL/ 6 mice undergoing 60 min of hepatic ischemia, IRF- 1 protein...- 1 mediates liver damage during ischemia- reperfusion injury. This IRF- 1- dependent inhibition of i... factor- 1. We have identified IRF- 1 expression in hepatocytes in vivo in sepsis. High impact information... / Synonyms: IRF-1
Sus scrofa
Gene: ... High impact information on IRF1 In contrast, in the mesenteric lymph node( MLN ), only expression of IRF1 and IFNG was significantly upregulated. Immunohistochemical analysis showed colocalization of IRF1, TLR2, and SOD1 protein in macrophages and confirmed the RNA expression data....
Gallus gallus
Gene: ... High impact information on IRF1 The cloning and functional characterization of a novel interferon... two putative binding sites for IRF- 1, but lacks NF- kappaB- binding sites, and it did not respond... with the chicken homolog( Ch- IRF- 1) of the mammalian transcription factor IRF- 1. The IRF- 1 proteins from...
Ovis aries
Gene: ... High impact information on IRF1 Electrophoretic mobility shift assays indicated that the- 2110 IRFE bound only IRF- 1, whereas the- 1877 IRFE and the- 1284 ISRE were functional in binding IRF- 1 and IRF... regulatory factors one( IRF- 1) and two( IRF- 2) are transcription factors induced by type I IFNs...
MeSH term: ... detection. The retention of IRF1 on the 5q- chromosome in these two cases has been confirmed by fluorescent in situ hybridization localization using an IRF1 cosmid. Cells transfected with DNA from both cosmid... the first intron of the TNF- beta gene and not in the TNF- alpha gene. The 190 kb of DNA linking all five CD...
Danio rerio
Gene: Synonyms: irf1
Danio rerio
Gene: Synonyms: IRF1


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