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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 37 documents. Results 1 - 10.

Homo sapiens
Gene: ... rabbit INSL3 antiserum localized Insl3 transcripts and immunoreactive INSL3 ligand to Leydig cells in all...Disease relevance of INSL3 The frequency of INSL3/ RLF gene mutations as a cause of cryptorchidism.... Subjects with severe testicular damage, such as men with severe infertility, produce low amount of INSL3...
Mus musculus
Gene: ... Disease relevance of Insl3 Mutations of Insl3 or Great cause cryptorchidism( undescended testes) in mice. In mutant females Insl3 over expression resulted in transabdominal descent of the ovaries to the low abdominal position with the subsequent development of inguinal hernia. Insl3 is responsible...
Rattus norvegicus
Gene: ... Disease relevance of Insl3 We generated( by genetic immunization) and validated a novel antirat Insl3 antibody, which we used to characterize immunoexpression of Insl3 in rat Leydig cells( LCs) from fetal life until adulthood and its relationship to cryptorchidism. High impact information on Insl3 We...
Homo sapiens
Gene: ... of the transmembrane region. INSL3, in turn, binds LGR8 expressed in germ cells to initiate the meiotic progression...) caused a significant dose- dependent transcriptional down- regulation of INSL- 3 and a marked up... cells and ovarian theca cells, we demonstrated the expression of the INSL3 receptor LGR8 in oocytes... / Synonyms: INSL3R
Bos taurus
Gene: ... High impact information on INSL3 Dynamic changes in the expression of relaxin- like factor( INSL3... of the RLF gene. Biological context of INSL3 Under conditions inducing luteal differentiation of theca cells... of luteinizing hormone( LH ), whereas the differentiation- specific up- regulation of INSL3 was suppressed by LH...
Canis lupus familiaris
Gene: ... Disease relevance of INSL3 Leydig cells specifically expressed RLF in the normal postpubertal... hernia. High impact information on INSL3 In the mature canine placenta, the trophoblast surrounding... and relaxin. Anatomical context of INSL3 Within the ovary, RLF, but not relaxin, was detected in follicular...
MeSH term: ... Disease relevance of Cryptorchidism We show here that mice mutant for Insl3 are viable, but exhibit... for Insl3. CONCLUSIONS: Measurements of serum mullerian inhibiting substance can be used to determine... with sporadic cryptorchidism. This phenotype suggests that INSL3 may have a role in the development of human...
MeSH term: ... The Insl3 gene( originally designated Ley I- L ), a member of the insulin- like superfamily...
Macaca mulatta
Gene

 

 
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