Your search matched a total of 71 documents. Results 1 - 10.
Homo sapiens
Gene: ... Disease relevance of JAG1 We demonstrate four distinct coding mutations in JAG1 from four Alagille... a JAG1 missense mutation( JAG1- G274D) that was previously identified in 13 individuals from an extended... expressivity in a large kindred, which demonstrates that mutation in JAG1 can cause hearing loss. We examined...
Mus musculus
Gene: ... that the Jag1 gene is required for the normal development of all six sensory organs within the inner ear. Our...Disease relevance of Jag1 Jag1 encodes a ligand in the Notch pathway and has been identified... role for N signaling during somitogenesis. High impact information on Jag1 We demonstrate that Jagged...
Danio rerio
Gene: ... High impact information on jag1a By contrast, analyses of mind bomb mutants and jagged morpholino- injected larvae suggest that Notch signaling principally regulates ductal differentiation of bipotential exocrine progenitors. Other interactions of jag1a The interaction of transmembrane Delta and Jagged... / Synonyms: jag1
Rattus norvegicus
Gene: ... Disease relevance of Jag1 Point mutations in Jagged- 1 gene are the cause for Alagille syndrome, associated with paucity of intrahepatic bile ducts. High impact information on Jag1 Finally, the biological... in myoblasts and prevents muscle cell differentiation. It has been proposed that Jag1 has a role in specifying...
MeSH term: ... members of two EXT1 families. Determining the complete exon- intron structure of JAG1 allowed detailed... inhibitors. Here we report that although all nonsense and frameshift mutations that cause premature... was found. All externally, suppressible frameshift mutations occur in glycine and proline codons to produce...
MeSH term: ... in the mouse. Systemic release of interleukin- 10 during orthotopic liver transplantation. The JAG1 gene...
MeSH term: ... Disease relevance of Biliary Tract Mutations in JAG1, encoding a Notch ligand, cause the Alagille... and liver all develop from the nearby foregut at almost the same time in mammals. If GSU does... in all three cell types lining the human biliary tree, with predominant expression in the gallbladder. We...
MeSH term: ... mutations in JAG1 from four Alagille syndrome families, providing evidence that it is the causal gene... Defective intracellular transport and processing of JAG1 missense mutations in Alagille syndrome. Mice heterozygous for the Jag1 null allele exhibit an eye dysmorphology similar to that of Cm /+ heterozygotes...
MeSH term: ... with tolazoline. All patients had congenital heart defects, including tetralogy of Fallot, ventricular septal... heart defects but with variable expressivity in a large kindred, which demonstrates that mutation in JAG1 can cause hearing loss. Chemical compound and disease context of Heart Defects, Congenital...
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Steven Johnsen and Donald R. Forsdyke and Kehinde Ross and Andrew Perry and Jonathan Eisen and A. Shimabukuro-Vornhagen and Giuseppe Rotondo and Gordon Laurie and Berkley Lynch and Kung-Hao Liang and Matthias Gstaiger and Thomas Pfeiffer and Marta Ramirez and Grant MacGregor and Jingyu Li and Fedik Rahimov and M El Gizouli and Marta Ramirez Gaite and Oswaldo Ribeiro-filho and Ralf Weigel and Bjoern Hamberger and Alexander Kanitz and Andreas Zankl and Chunming Ding and Maruf Yunus and Jonathan S. Berg and Michael Cariaso and Zakir Thomas and Monique Timberlake-Brady and LC Dore and Nan Shen and R. Eric Collins and Kuang-Mao Chiang and Brendan McMahon and John Chew and Wen-Ming Yang and Robert Hoffmann and J.B. Stewart and Manuela Cucerea and Ignacio García and William James and Thomas Kelder and Gregory Melahn and YINGDE ZHU and Andres Muro and Gabriel Santpere and Jeff Freilich and Junbin Qian and Steffen Poulsen and Eric Villard and Rafael Sidi and Grant Cramer and Chris Sander and Alexandre Chigaev and Florian Uhle and Carl Fulp and Andrew Brown and Xiaozhu Zhou and Corina Dutu and Hilary Spencer and david germano and Abbas Dehghan and Eung-ju PARK and Chris Sander and Albert Vilella and Miao Tian and Anjali Bheda and Michael Nevels and Jun Liu and D Delano and Chitose Taya and Soomi Cheong and David Kavanagh and Maha Karnoub and Hilmar Lapp and Christian Pallasch and Daniel Mietchen and Biju Balakrishnan and Keith Ashman and Juan Carlos Sobrino and Anshu Bhardwaj and Grzegorz Wickiel and Matthew Day and Anthony Sebastian and Vedran Katavic and Liang Long and Barry Wanner and Sarah Snelling and Fernando Montanes and Omobosede Fashedemi and Gustavo Cervantes and Manoj Kumar and Edward D Great and Paul Paukstelis and Roy Soetikno and Ana I Caño-Delgado and Minsoo Choi and Lei Wang and Brenda Riley and A Michelle Moon and Jon Moulton and Mahmoud Elshahawy and Meagan Gillespie and Banundari Rachmawati and Qian Han and Eric Danner and Xavier Fouillet and Madhusudhan Acharya and Brian Young and Chandra Sekhar Mukhopadhyay and shrawan bhattacharjee and Marieke van der Linden and cj hoban and Sandi Pniauskas and jackie gao and Metin Bilgin and Gillian L. Dalgliesh and Karl Wotton and Iveta Herichova and Yuji Morita and Marta Hernandez and Gregor Krings and Marco Briones and Tim D. Smith and Yiumo Michael Chan and Zhenyu Guo and Barry Barclay and Hong Wang and tarali chowdhury and Tilman Brummer and Nuno Faria and Tamir Ben David and Myles Axton and Yannick Fonseca and Francis Castets and Modesto Redrejo-Rodríguez and Bruce Herron and Toshio Fujita and Elena Puccetti and Zhang Zhang and John Osborne and Illes J Farkas and Fernando Andres and Phyllis Pugh and Jonathan Court and Tim Vickers and Nir Friedman and Holger Dick and Ya-Chen Liang and Jonathan Froehlich and Haitham Sobhy and David Abraham and Stephane Krief and Yaroslav Nikolaev and Qiping Feng and d gupta and R Thapar and Susan Wee and Michael Rehman and SOUMITRA GHOSH and Mohamed Eweida and Cedric Uytingco and Nie hongchuan and David Steenblock and Mark A. Kukucka and Zoli Fekete and Sergei Kozlov and Javier Jara and Osama Naguib and Felix Benninger and jean-marc lo-guidice and VASUDEVA BHAT and Anne O. Summers and Bjoern Titz and Anna Levine and Klas Udekwu and Robert Hoffmann
