The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Alagille Syndrome

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Alagille Syndrome


High impact information on Alagille Syndrome


Chemical compound and disease context of Alagille Syndrome


Biological context of Alagille Syndrome


Anatomical context of Alagille Syndrome


Gene context of Alagille Syndrome


Analytical, diagnostic and therapeutic context of Alagille Syndrome


  1. Growth hormone insensitivity associated with elevated circulating growth hormone-binding protein in children with Alagille syndrome and short stature. Bucuvalas, J.C., Horn, J.A., Carlsson, L., Balistreri, W.F., Chernausek, S.D. J. Clin. Endocrinol. Metab. (1993) [Pubmed]
  2. Ocular anomalies in the alagille syndrome (arteriohepatic dysplasia). Brodsky, M.C., Cunniff, C. Ophthalmology (1993) [Pubmed]
  3. Craniosynostosis in Alagille syndrome. Kamath, B.M., Stolle, C., Bason, L., Colliton, R.P., Piccoli, D.A., Spinner, N.B., Krantz, I.D. Am. J. Med. Genet. (2002) [Pubmed]
  4. Severe hypodontia and oral xanthomas in Alagille syndrome. Ho, N.C., Lacbawan, F., Francomano, C.A., Ho, V. Am. J. Med. Genet. (2000) [Pubmed]
  5. Hepatobiliary scintigraphy and the string test in the evaluation of neonatal cholestasis. Rosenthal, P., Miller, J.H., Sinatra, F.R. J. Pediatr. Gastroenterol. Nutr. (1989) [Pubmed]
  6. Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1. Li, L., Krantz, I.D., Deng, Y., Genin, A., Banta, A.B., Collins, C.C., Qi, M., Trask, B.J., Kuo, W.L., Cochran, J., Costa, T., Pierpont, M.E., Rand, E.B., Piccoli, D.A., Hood, L., Spinner, N.B. Nat. Genet. (1997) [Pubmed]
  7. Mutations in the human Jagged1 gene are responsible for Alagille syndrome. Oda, T., Elkahloun, A.G., Pike, B.L., Okajima, K., Krantz, I.D., Genin, A., Piccoli, D.A., Meltzer, P.S., Spinner, N.B., Collins, F.S., Chandrasekharappa, S.C. Nat. Genet. (1997) [Pubmed]
  8. Abnormal lipoprotein pattern in patients with Alagille syndrome depends on Icterus severity. Davit-Spraul, A., Pourci, M.L., Atger, V., Cambillau, M., Hadchouel, M., Moatti, N., Legrand, A. Gastroenterology (1996) [Pubmed]
  9. Late recurrence of a hepatocellular carcinoma in a patient with incomplete Alagille syndrome. Le Bail, B., Bioulac-Sage, P., Arnoux, R., Perissat, J., Saric, J., Balabaud, C. Gastroenterology (1990) [Pubmed]
  10. Cholesterol efflux from Fu5AH cells to the serum of patients with Alagille syndrome. Importance of the hdl-phospholipids/free cholesterol ratio and of the hdl size distribution. Davit-Spraul, A., Atger, V., Pourci, M.L., Hadchouel, M., Legrand, A., Moatti, N. J. Lipid Res. (1999) [Pubmed]
  11. Investigation of serum bile acids; seven patients with Alagille syndrome. Obinata, K., Nakatsu, N., Watanabe, T., Niijima, S., Arisaka, O., Sasaki, H., Nittono, H., Yabuta, K., Miyano, T. Eur. J. Pediatr. (1985) [Pubmed]
  12. 2-Deoxy-D-glucose uptake and fatty acid content in fibroblast cultures from children with syndromic paucity of interlobular bile ducts (Alagille syndrome). Couturier, M., Lemonnier, F. J. Inherit. Metab. Dis. (1991) [Pubmed]
  13. Bile acid metabolism in mild arteriohepatic dysplasia. Collins, D.M., Shannon, F.T., Campbell, C.B. Australian and New Zealand journal of medicine. (1981) [Pubmed]
  14. Use of ursodeoxycholic acid in the treatment of arteriohepatic dysplasia. Kay, M.H., Wyllie, R., Steffen, R.M. Clinical pediatrics. (1996) [Pubmed]
  15. Defective intracellular transport and processing of JAG1 missense mutations in Alagille syndrome. Morrissette, J.D., Colliton, R.P., Spinner, N.B. Hum. Mol. Genet. (2001) [Pubmed]
  16. Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1. Xue, Y., Gao, X., Lindsell, C.E., Norton, C.R., Chang, B., Hicks, C., Gendron-Maguire, M., Rand, E.B., Weinmaster, G., Gridley, T. Hum. Mol. Genet. (1999) [Pubmed]
  17. Expression of Notch-1 and its ligand Jagged-1 in rat liver during liver regeneration. Köhler, C., Bell, A.W., Bowen, W.C., Monga, S.P., Fleig, W., Michalopoulos, G.K. Hepatology (2004) [Pubmed]
  18. Interstitial deletion of the short arm of chromosome 20 in arteriohepatic dysplasia (Alagille syndrome). Zhang, F., Deleuze, J.F., Aurias, A., Dutrillaux, A.M., Hugon, R.N., Alagille, D., Thomas, G., Hadchouel, M. J. Pediatr. (1990) [Pubmed]
  19. Monozygotic twins with a severe form of Alagille syndrome and phenotypic discordance. Kamath, B.M., Krantz, I.D., Spinner, N.B., Heubi, J.E., Piccoli, D.A. Am. J. Med. Genet. (2002) [Pubmed]
  20. The role of notch signaling in the development of intrahepatic bile ducts. Kodama, Y., Hijikata, M., Kageyama, R., Shimotohno, K., Chiba, T. Gastroenterology (2004) [Pubmed]
  21. Human jagged 1 mutants cause liver defect in Alagille syndrome by overexpression of hepatocyte growth factor. Yuan, Z.R., Kobayashi, N., Kohsaka, T. J. Mol. Biol. (2006) [Pubmed]
  22. Hepatocellular carcinoma associated with arteriohepatic dysplasia in a 4-year-old girl. Békássy, A.N., Garwicz, S., Wiebe, T., Hägerstrand, I., Jensen, O.A. Med. Pediatr. Oncol. (1992) [Pubmed]
  23. Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders. Tommerup, N., Vissing, H. Genomics (1995) [Pubmed]
  24. SR-BI- and ABCA1-mediated cholesterol efflux to serum from patients with Alagille syndrome. Yancey, P.G., Asztalos, B.F., Stettler, N., Piccoli, D., Williams, D.L., Connelly, M.A., Rothblat, G.H. J. Lipid Res. (2004) [Pubmed]
  25. Identification, characterization, and chromosomal localization of the human homolog (hES) of ES/130. Basson, C.T., MacRae, C.A., Schoenberg-Fejzo, M., Morton, C.C., Spinner, N.B., Genin, A., Krug, E., Seidman, J.G., Seidman, C.E. Genomics (1996) [Pubmed]
  26. Distinct hepatic retention of Tc-99m IDA in arteriohepatic dysplasia (Alagille syndrome). Aburano, T., Yokoyama, K., Takayama, T., Tonami, N., Hisada, K. Clinical nuclear medicine. (1989) [Pubmed]
  27. Alagille syndrome in a family with duplication 20p11. Moog, U., Engelen, J., Albrechts, J., Hoorntje, T., Hendrikse, F., Schrander-Stumpel, C. Clin. Dysmorphol. (1996) [Pubmed]
WikiGenes - Universities