Your search matched a total of 232 documents. Results 1 - 10.
Homo sapiens
Gene: ... acute lymphoblastic leukemia( BCP- ALL). JAK2 V617F mutation contributed to hemoglobin, aquagenic...Disease relevance of JAK2 Mice deficient in TYK2 developed Abelson- induced B lymphoid leukemia/ lymphoma as well as TEL- JAK2- induced T lymphoid leukemia with a higher incidence and shortened latency... / Synonyms: JAK-2; Tyrosine-protein kinase JAK2
Mus musculus
Gene: ... Disease relevance of Jak2 Collectively, our data suggest that Jak2 is differentiation- inducing... of the Jak2- Stat5 pathway in breast cancer. Janus kinase 2: a critical target in chronic myelogenous...- phosphorylation levels of JAK2 and STAT5a/ b increased significantly, reaching similar values in normal and dwarf... / Synonyms: JAK-2; Tyrosine-protein kinase JAK2
Rattus norvegicus
Gene: ... Disease relevance of Jak2 Furthermore, this report identifies Jak2 as a potential therapeutic... cardiomyocytes, produced apoptosis that was dependent upon activation of Jak2. In conclusion, our studies demonstrate that hyperglycemia induces activation of JAK2 and the STATs in vivo via an ANG II- dependent... / Synonyms: JAK-2; Tyrosine-protein kinase JAK2
Canis lupus familiaris
Gene: ... High impact information on JAK2 We found that TGF- beta inhibited tyrosine phosphorylation of Lyn, Jak2, and a 44- kDa MAP kinase. Mechanism of inhibition of eosinophil activation by transforming growth factor- beta. Inhibition of Lyn, MAP, Jak2 kinases and STAT1 nuclear factor....
Gallus gallus
Gene: ... Disease relevance of JAK2 In this study, GH- responsive, JAK2 immunoreactive proteins were first assessed in an avian hepatoma cell line( LMH). High impact information on JAK2 These findings indicate that PRL- mediated stimulation of c- Src was independent of Jak2 activation and of receptor phosphorylation...
Sus scrofa
Gene: ... High impact information on JAK2 Mapping of the porcine JAK2, JAK3 and TYK2 genes using somatic cell... and JAK2, while MAP kinase phosphorylation was unaffected. It was found that the mutation of serine... of JAK2, while the mutation of tyrosine to histidine at position 168 increased the protein synthesis...
Danio rerio
Gene: ... Disease relevance of jak2a MATERIALS AND METHODS: To assess whether zebrafish could be utilized as a suitable model for the study of myeloid oncogenesis, we generated a zebrafish tel- jak2a fusion oncoprotein based on that seen in a case of chronic myeloid leukemia. High impact information on jak2a Gene...
MeSH term: ... or undergoes apoptosis upon Fas ligand stimulation. We have examined the functional relevance of Lyn, Jak2... activities on eosinophils. All three patients had elevated serum and urinary levels of this protein...
Homo sapiens
Gene: ... in Drosophila. Chemical compound and disease context of JAK1 AG490( JAK2 specific) induced apoptosis in DU145... cadmium( CdCl2) inhibited ciliary neurotrophic factor( CNTF )- mediated Jak1 and Jak2 tyrosine kinase...1 was dependent on the activation of JAK2. Moreover, IL- 5- induced dimerization of IL- 5R subunits...
Links to contributing authors:
Steven Johnsen and Donald R. Forsdyke and Kehinde Ross and Andrew Perry and Jonathan Eisen and A. Shimabukuro-Vornhagen and Giuseppe Rotondo and Gordon Laurie and Berkley Lynch and Kung-Hao Liang and Matthias Gstaiger and Thomas Pfeiffer and Marta Ramirez and Grant MacGregor and Jingyu Li and Fedik Rahimov and M El Gizouli and Marta Ramirez Gaite and Oswaldo Ribeiro-filho and Ralf Weigel and Bjoern Hamberger and Alexander Kanitz and Andreas Zankl and Chunming Ding and Maruf Yunus and Jonathan S. Berg and Michael Cariaso and Zakir Thomas and Monique Timberlake-Brady and LC Dore and Nan Shen and R. Eric Collins and Kuang-Mao Chiang and Brendan McMahon and John Chew and Wen-Ming Yang and Robert Hoffmann and J.B. Stewart and Manuela Cucerea and Ignacio García and William James and Thomas Kelder and Gregory Melahn and YINGDE ZHU and Andres Muro and Gabriel Santpere and Jeff Freilich and Junbin Qian and Steffen Poulsen and Eric Villard and Rafael Sidi and Grant Cramer and Chris Sander and Alexandre Chigaev and Florian Uhle and Carl Fulp and Andrew Brown and Xiaozhu Zhou and Corina Dutu and Hilary Spencer and david germano and Abbas Dehghan and Eung-ju PARK and Chris Sander and Albert Vilella and Miao Tian and Anjali Bheda and Michael Nevels and Jun Liu and D Delano and Chitose Taya and Soomi Cheong and David Kavanagh and Maha Karnoub and Hilmar Lapp and Christian Pallasch and Daniel Mietchen and Biju Balakrishnan and Keith Ashman and Juan Carlos Sobrino and Anshu Bhardwaj and Grzegorz Wickiel and Matthew Day and Anthony Sebastian and Vedran Katavic and Liang Long and Barry Wanner and Sarah Snelling and Fernando Montanes and Omobosede Fashedemi and Gustavo Cervantes and Manoj Kumar and Edward D Great and Paul Paukstelis and Roy Soetikno and Ana I Caño-Delgado and Minsoo Choi and Lei Wang and Brenda Riley and A Michelle Moon and Jon Moulton and Mahmoud Elshahawy and Meagan Gillespie and Banundari Rachmawati and Qian Han and Eric Danner and Xavier Fouillet and Madhusudhan Acharya and Brian Young and Chandra Sekhar Mukhopadhyay and shrawan bhattacharjee and Marieke van der Linden and cj hoban and Sandi Pniauskas and jackie gao and Metin Bilgin and Gillian L. Dalgliesh and Karl Wotton and Iveta Herichova and Yuji Morita and Marta Hernandez and Gregor Krings and Marco Briones and Tim D. Smith and Yiumo Michael Chan and Zhenyu Guo and Barry Barclay and Hong Wang and tarali chowdhury and Tilman Brummer and Nuno Faria and Tamir Ben David and Myles Axton and Yannick Fonseca and Francis Castets and Modesto Redrejo-Rodríguez and Bruce Herron and Toshio Fujita and Elena Puccetti and Zhang Zhang and John Osborne and Illes J Farkas and Fernando Andres and Phyllis Pugh and Jonathan Court and Tim Vickers and Nir Friedman and Holger Dick and Ya-Chen Liang and Jonathan Froehlich and Haitham Sobhy and David Abraham and Stephane Krief and Yaroslav Nikolaev and Qiping Feng and d gupta and R Thapar and Susan Wee and Michael Rehman and SOUMITRA GHOSH and Mohamed Eweida and Cedric Uytingco and Nie hongchuan and David Steenblock and Mark A. Kukucka and Zoli Fekete and Sergei Kozlov and Javier Jara and Osama Naguib and Felix Benninger and jean-marc lo-guidice and VASUDEVA BHAT and Anne O. Summers and Bjoern Titz and Anna Levine and Klas Udekwu and Robert Hoffmann







