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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 49 documents. Results 1 - 10.

Homo sapiens
Gene: ... Disease relevance of LIMK1 Because ELN mutations cause vascular disease but not cognitive abnormalities, these data implicate LIMK1 hemizygosity in imparied visuospatial constructive cognition. Our.... 2 in prostate cancer, suggesting a possible gain in LIMK1 DNA( 7q11. 23). The" native" LIMK1 protein... / Synonyms: LIMK-1
Drosophila melanogaster
Gene: ... High impact information on LIMK1 Cofilin function in axon growth is inhibited by LIM kinase and activated by Slingshot phosphatase. LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1... expression and morphogenesis during Drosophila metamorphosis. Anatomical context of LIMK1 When expressed... / Synonyms: D-LIMK1; LIMK-1; dLIMK1
Rattus norvegicus
Gene: ... Disease relevance of Limk1 We resolve this paradox by showing that the effects of LIMK1 expression... of the output of the cofilin pathway. Genetic studies have implicated a mutation of LIMK1 as a causative factor... information on Limk1 Phosphorylation by LIM- kinase 1 inactivates cofilin, leading to accumulation of actin... / Synonyms: LIMK-1
Mus musculus
Gene: ... and phosphorylates serine, threonine and tyrosine residues in vitro. Although Limk1 and LIMK contain all motifs found...Disease relevance of Limk1 In addition, abnormal expression of LIMK- 1 is associated with Williams syndrome, a mental disorder with profound deficits in visuospatial cognition. LIM kinase 1( LIMK1) controls... / Synonyms: LIMK-1
Gallus gallus
Gene: ... High impact information on LIMK1 The repressive effects on growth cone behavior by LIMK1 expression were significantly rescued by the coexpression of S3A- cofilin or SSH1. Control of growth cone motility and morphology by LIM kinase and Slingshot via phosphorylation and dephosphorylation of cofilin....
MeSH term: ... cellular differentiation. When expressed in cultured cells, LIMK- 1 induces actin reorganization... cultured cells. All 23 serums with immune complex levels greater than 20 microgram per milliliter were...
MeSH term: ... implicate LIMK1 hemizygosity in imparied visuospatial constructive cognition. Here we describe two families...
MeSH term: ... of a dinucleotide repeat polymorphism. The recent findings that knockout mice lacking LIMK1 or CLIP- 115 have... with two TFII- I- like helix- loop- helix repeats. The association of the Limk1 gene with Williams Syndrome...). Comparative genomic sequence analysis of the Williams syndrome region( LIMK1- RFC2) of human chromosome 7q11...
Sus scrofa
Gene
Macaca mulatta
Gene

 

 
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