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MeSH Review

Cells, Cultured

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Disease relevance of Cells, Cultured


Psychiatry related information on Cells, Cultured


High impact information on Cells, Cultured

  • This receptor, called scavenger receptor class B type I (SR-BI), is a fatty acylated glycoprotein that can cluster in caveolae-like domains on the surfaces of cultured cells [9].
  • Overexpression of JMJD2A but not a catalytically inactive mutant reduced H3-K9/K36 trimethylation levels in cultured cells [10].
  • Expression of mutant HSPB8 in cultured cells promoted formation of intracellular aggregates [11].
  • Furthermore, SSH and the hSSHs dephosphorylated P cofilin in cultured cells and in cell-free assays [12].
  • UCH-L1, especially those variants linked to higher susceptibility to PD, causes the accumulation of alpha-synuclein in cultured cells, an effect that cannot be explained by its recognized hydrolase activity [13].

Chemical compound and disease context of Cells, Cultured


Biological context of Cells, Cultured


Anatomical context of Cells, Cultured


Associations of Cells, Cultured with chemical compounds


Gene context of Cells, Cultured


Analytical, diagnostic and therapeutic context of Cells, Cultured


  1. Identification of invasin: a protein that allows enteric bacteria to penetrate cultured mammalian cells. Isberg, R.R., Voorhis, D.L., Falkow, S. Cell (1987) [Pubmed]
  2. Binding of soluble immune complexes in serum of patients with Hodgkin's disease to tissue cultures derived from the tumor. Long, J.C., Hall, C.L., Brown, C.A., Stamatos, C., Weitzman, S.A., Carey, K. N. Engl. J. Med. (1977) [Pubmed]
  3. Localization of serum-derived alpha 2 macroglobulin in cultured cells and decrease after Moloney sarcoma virus transformation. Pastan, I., Willingham, M., Anderson, W., Gallo, M. Cell (1977) [Pubmed]
  4. Adenosine 3',5'-monophosphate analogs promote a circular morphology of cultured Schwannoma cells. Sheppard, J.R., Hudson, T.H., Larson, J.R. Science (1975) [Pubmed]
  5. A cancer-associated lactate dehydrogenase is expressed in normal retina. Saavedra, R.A., Anderson, G.R. Science (1983) [Pubmed]
  6. Dominant-negative inhibition of prion replication in transgenic mice. Perrier, V., Kaneko, K., Safar, J., Vergara, J., Tremblay, P., DeArmond, S.J., Cohen, F.E., Prusiner, S.B., Wallace, A.C. Proc. Natl. Acad. Sci. U.S.A. (2002) [Pubmed]
  7. Evidence that production and release of amyloid beta-protein involves the endocytic pathway. Koo, E.H., Squazzo, S.L. J. Biol. Chem. (1994) [Pubmed]
  8. Glutamic acid decarboxylase and gamma-aminobutyric acid in Huntington's disease fibroblasts and other cultured cells, determined by a [3H]muscimol radioreceptor assay. Hamel, E., Goetz, I.E., Roberts, E. J. Neurochem. (1981) [Pubmed]
  9. Charting the fate of the "good cholesterol": identification and characterization of the high-density lipoprotein receptor SR-BI. Krieger, M. Annu. Rev. Biochem. (1999) [Pubmed]
  10. Reversal of Histone Lysine Trimethylation by the JMJD2 Family of Histone Demethylases. Whetstine, J.R., Nottke, A., Lan, F., Huarte, M., Smolikov, S., Chen, Z., Spooner, E., Li, E., Zhang, G., Colaiacovo, M., Shi, Y. Cell (2006) [Pubmed]
  11. Hot-spot residue in small heat-shock protein 22 causes distal motor neuropathy. Irobi, J., Van Impe, K., Seeman, P., Jordanova, A., Dierick, I., Verpoorten, N., Michalik, A., De Vriendt, E., Jacobs, A., Van Gerwen, V., Vennekens, K., Mazanec, R., Tournev, I., Hilton-Jones, D., Talbot, K., Kremensky, I., Van Den Bosch, L., Robberecht, W., Van Vandekerckhove, J., Broeckhoven, C., Gettemans, J., De Jonghe, P., Timmerman, V. Nat. Genet. (2004) [Pubmed]
  12. Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilin. Niwa, R., Nagata-Ohashi, K., Takeichi, M., Mizuno, K., Uemura, T. Cell (2002) [Pubmed]
  13. The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility. Liu, Y., Fallon, L., Lashuel, H.A., Liu, Z., Lansbury, P.T. Cell (2002) [Pubmed]
  14. Effect of bile salts and of fusidic acid on HIV-1 infection of cultured cells. Lloyd, G., Atkinson, T., Sutton, P.M. Lancet (1988) [Pubmed]
  15. Interactions of Semliki Forest virus spike glycoprotein rosettes and vesicles with cultured cells. Marsh, M., Bolzau, E., White, J., Helenius, A. J. Cell Biol. (1983) [Pubmed]
  16. Codistribution of heparan sulfate proteoglycan, laminin, and fibronectin in the extracellular matrix of normal rat kidney cells and their coordinate absence in transformed cells. Hayman, E.G., Oldberg, A., Martin, G.R., Ruoslahti, E. J. Cell Biol. (1982) [Pubmed]
  17. Organization of actin in the leading edge of cultured cells: influence of osmium tetroxide and dehydration on the ultrastructure of actin meshworks. Small, J.V. J. Cell Biol. (1981) [Pubmed]
  18. Heat shock induces protein tyrosine phosphorylation in cultured cells. Maher, P.A., Pasquale, E.B. J. Cell Biol. (1989) [Pubmed]
  19. Expanded polyglutamine in the Machado-Joseph disease protein induces cell death in vitro and in vivo. Ikeda, H., Yamaguchi, M., Sugai, S., Aze, Y., Narumiya, S., Kakizuka, A. Nat. Genet. (1996) [Pubmed]
  20. Jun-Fos and receptors for vitamins A and D recognize a common response element in the human osteocalcin gene. Schüle, R., Umesono, K., Mangelsdorf, D.J., Bolado, J., Pike, J.W., Evans, R.M. Cell (1990) [Pubmed]
  21. The Drosophila gene hid is a direct molecular target of Ras-dependent survival signaling. Bergmann, A., Agapite, J., McCall, K., Steller, H. Cell (1998) [Pubmed]
  22. Recent insights in phosphatidylinositol signaling. Majerus, P.W., Ross, T.S., Cunningham, T.W., Caldwell, K.K., Jefferson, A.B., Bansal, V.S. Cell (1990) [Pubmed]
  23. Regulation of invasive cell behavior by taiman, a Drosophila protein related to AIB1, a steroid receptor coactivator amplified in breast cancer. Bai, J., Uehara, Y., Montell, D.J. Cell (2000) [Pubmed]
  24. Relationships between fibronectin (LETS protein) and actin. Hynes, R.O., Destree, A.T. Cell (1978) [Pubmed]
  25. Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis. Yin, X.M., Wang, K., Gross, A., Zhao, Y., Zinkel, S., Klocke, B., Roth, K.A., Korsmeyer, S.J. Nature (1999) [Pubmed]
  26. Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice. Ilić, D., Furuta, Y., Kanazawa, S., Takeda, N., Sobue, K., Nakatsuji, N., Nomura, S., Fujimoto, J., Okada, M., Yamamoto, T. Nature (1995) [Pubmed]
  27. Activation of latent Ca2+ channels in renal epithelial cells by parathyroid hormone. Bacskai, B.J., Friedman, P.A. Nature (1990) [Pubmed]
  28. Biology of the interleukin-2 receptor. Nelson, B.H., Willerford, D.M. Adv. Immunol. (1998) [Pubmed]
  29. Hydrolase and serum treatment of normal chick embryo cells: effects on hexose transport. Hale, A.H., Weber, M.J. Cell (1975) [Pubmed]
  30. Vitellogenin gene expression in male Xenopus hepatocytes during primary and secondary stimulation with estrogen in cell cultures. Searle, P.F., Tata, J.R. Cell (1981) [Pubmed]
  31. Control of nucleolar RNA synthesis by the intracellular pool sizes of ATP and GTP. Grummt, I., Grummt, F. Cell (1976) [Pubmed]
  32. Homocystinuria and megaloblastic anemia responsive to vitamin B12 therapy. An inborn error of metabolism due to a defect in cobalamin metabolism. Schuh, S., Rosenblatt, D.S., Cooper, B.A., Schroeder, M.L., Bishop, A.J., Seargeant, L.E., Haworth, J.C. N. Engl. J. Med. (1984) [Pubmed]
  33. Spontaneous glycosylation of glycosaminoglycan substrates by adherent fibroblasts. Turley, E.A., Roth, S. Cell (1979) [Pubmed]
  34. hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. Meyerson, M., Counter, C.M., Eaton, E.N., Ellisen, L.W., Steiner, P., Caddle, S.D., Ziaugra, L., Beijersbergen, R.L., Davidoff, M.J., Liu, Q., Bacchetti, S., Haber, D.A., Weinberg, R.A. Cell (1997) [Pubmed]
  35. Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization. Yang, N., Higuchi, O., Ohashi, K., Nagata, K., Wada, A., Kangawa, K., Nishida, E., Mizuno, K. Nature (1998) [Pubmed]
  36. Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor. Uehara, Y., Minowa, O., Mori, C., Shiota, K., Kuno, J., Noda, T., Kitamura, N. Nature (1995) [Pubmed]
  37. Chibby, a nuclear beta-catenin-associated antagonist of the Wnt/Wingless pathway. Takemaru, K., Yamaguchi, S., Lee, Y.S., Zhang, Y., Carthew, R.W., Moon, R.T. Nature (2003) [Pubmed]
  38. Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4. Suzuki, N., Suzuki, S., Duncan, G.S., Millar, D.G., Wada, T., Mirtsos, C., Takada, H., Wakeham, A., Itie, A., Li, S., Penninger, J.M., Wesche, H., Ohashi, P.S., Mak, T.W., Yeh, W.C. Nature (2002) [Pubmed]
  39. Monoclonal antibody to 5-bromo- and 5-iododeoxyuridine: A new reagent for detection of DNA replication. Gratzner, H.G. Science (1982) [Pubmed]
  40. In vitro studies on lymphocyte differentiation. I. Long term in vitro culture of cells giving rise to functional lymphocytes in irradiated mice. Schrader, J.W., Schrader, S. J. Exp. Med. (1978) [Pubmed]
  41. Expression of vasoactive intestinal polypeptide and amylase in a human parotid gland adenocarcinoma cell line in culture. Hayashi, Y., Yanagawa, T., Yoshida, H., Azuma, M., Nishida, T., Yura, Y., Sato, M. J. Natl. Cancer Inst. (1987) [Pubmed]
  42. Role of endogenous prostaglandin E2 in erythropoietin production and dome formation by human renal carcinoma cells in culture. Hagiwara, M., McNamara, D.B., Chen, I.L., Fisher, J.W. J. Clin. Invest. (1984) [Pubmed]
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