Your search matched a total of 41 documents. Results 1 - 10.
Homo sapiens
Gene: ... Disease relevance of MBD4 Of the MSI- H polyps, 2 had a somatic frameshift mutation of the MBD4 gene, 1 of MSH6, 1 of BAX, and 2 of transforming growth factor betaRII. CONCLUSIONS: Mutations in MBD4... in the same patient. Somatic frameshift mutations in the MBD4 gene of sporadic colon cancers with mismatch... / Synonyms: Methyl-CpG-binding protein MBD4
Mus musculus
Gene: ... High impact information on Mbd4 Within the nucleus, FADD interacted with the methyl- CpG binding domain protein 4( MBD4 ), which excises thymine from GT mismatches in methylated regions of chromatin... link between genome surveillance and apoptosis. Although Mbd4 inactivation did not increase... / Synonyms: Methyl-CpG-binding protein MBD4
MeSH term: ... the gene for the methyl- CpG binding thymine glycosylase, MBD4, in over 40% of microsatellite unstable... inhibitors. Here we report that although all nonsense and frameshift mutations that cause premature... was found. All externally, suppressible frameshift mutations occur in glycine and proline codons to produce...
MeSH term: ... during hepatocarcinogenesis, and that reduced expression of MBD4 may play a role in malignant progression... differential methylation. Because not all PIA cells are positive for GSTP1 protein, we hypothesized that some... sequencing method indicate that the BRCA1 CpG island is regionally methylated in all human tissues analyzed...
Chemical compound: ... in favor of thymine( 8 %). The thymine glycosylase MBD4 can bind to the product of deamination...G- binding protein MBD4. Analytical, diagnostic and therapeutic context of thymine In an attempt to find...) that displays unlimited growth potential when all of the thymine residues in nuclear DNA are replaced... / Synonyms: PubChem9313
Chemical compound: ... , and a structure revision of isatan B. Gene context of thymine We tested this hypothesis by analyzing Mbd4 -/- mice.... The mammalian protein MBD4 contains a methyl- CpG binding domain and can enzymatically remove thymine( T...
Mus musculus
Gene: ... . High impact information on Defb4 The base excision repair( BER) enzyme MED1( also known as MBD4) interacts with the MMR protein MLH1. The MBD4 active site is situated in a cleft that likely orients and binds DNA. MBD- 4 mRNA was expressed in the esophagus, tongue, and trachea but not in any of 20 other... / Synonyms: MBD-4
MeSH term: ... , as analyzed by an in vitro switch assay and by in vivo immunizations, is unaffected in Mbd4 (-/-) mice... antibody, all use members of the same gene families; remarkably, they also express identical amino acid.... All patients received the same dose and schedule of vaccine immunizations; those randomized...
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Steven Johnsen and Donald R. Forsdyke and Kehinde Ross and Andrew Perry and Jonathan Eisen and A. Shimabukuro-Vornhagen and Giuseppe Rotondo and Gordon Laurie and Berkley Lynch and Kung-Hao Liang and Matthias Gstaiger and Thomas Pfeiffer and Marta Ramirez and Grant MacGregor and Jingyu Li and Fedik Rahimov and M El Gizouli and Marta Ramirez Gaite and Oswaldo Ribeiro-filho and Ralf Weigel and Bjoern Hamberger and Alexander Kanitz and Andreas Zankl and Chunming Ding and Maruf Yunus and Jonathan S. Berg and Michael Cariaso and Zakir Thomas and Monique Timberlake-Brady and LC Dore and Nan Shen and R. Eric Collins and Kuang-Mao Chiang and Brendan McMahon and John Chew and Wen-Ming Yang and Robert Hoffmann and J.B. Stewart and Manuela Cucerea and Ignacio García and William James and Thomas Kelder and Gregory Melahn and YINGDE ZHU and Andres Muro and Gabriel Santpere and Jeff Freilich and Junbin Qian and Steffen Poulsen and Eric Villard and Rafael Sidi and Grant Cramer and Chris Sander and Alexandre Chigaev and Florian Uhle and Carl Fulp and Andrew Brown and Xiaozhu Zhou and Corina Dutu and Hilary Spencer and david germano and Abbas Dehghan and Eung-ju PARK and Chris Sander and Albert Vilella and Miao Tian and Anjali Bheda and Michael Nevels and Jun Liu and D Delano and Chitose Taya and Soomi Cheong and David Kavanagh and Maha Karnoub and Hilmar Lapp and Christian Pallasch and Daniel Mietchen and Biju Balakrishnan and Keith Ashman and Juan Carlos Sobrino and Anshu Bhardwaj and Grzegorz Wickiel and Matthew Day and Anthony Sebastian and Vedran Katavic and Liang Long and Barry Wanner and Sarah Snelling and Fernando Montanes and Omobosede Fashedemi and Gustavo Cervantes and Manoj Kumar and Edward D Great and Paul Paukstelis and Roy Soetikno and Ana I Caño-Delgado and Minsoo Choi and Lei Wang and Brenda Riley and A Michelle Moon and Jon Moulton and Mahmoud Elshahawy and Meagan Gillespie and Banundari Rachmawati and Qian Han and Eric Danner and Xavier Fouillet and Madhusudhan Acharya and Brian Young and Chandra Sekhar Mukhopadhyay and shrawan bhattacharjee and Marieke van der Linden and cj hoban and Sandi Pniauskas and jackie gao and Metin Bilgin and Gillian L. Dalgliesh and Karl Wotton and Iveta Herichova and Yuji Morita and Marta Hernandez and Gregor Krings and Marco Briones and Tim D. Smith and Yiumo Michael Chan and Zhenyu Guo and Barry Barclay and Hong Wang and tarali chowdhury and Tilman Brummer and Nuno Faria and Tamir Ben David and Myles Axton and Yannick Fonseca and Francis Castets and Modesto Redrejo-Rodríguez and Bruce Herron and Toshio Fujita and Elena Puccetti and Zhang Zhang and John Osborne and Illes J Farkas and Fernando Andres and Phyllis Pugh and Jonathan Court and Tim Vickers and Nir Friedman and Holger Dick and Ya-Chen Liang and Jonathan Froehlich and Haitham Sobhy and David Abraham and Stephane Krief and Yaroslav Nikolaev and Qiping Feng and d gupta and R Thapar and Susan Wee and Michael Rehman and SOUMITRA GHOSH and Mohamed Eweida and Cedric Uytingco and Nie hongchuan and David Steenblock and Mark A. Kukucka and Zoli Fekete and Sergei Kozlov and Javier Jara and Osama Naguib and Felix Benninger and jean-marc lo-guidice and VASUDEVA BHAT and Anne O. Summers and Bjoern Titz and Anna Levine and Klas Udekwu and Robert Hoffmann
