Your search matched a total of 147 documents. Results 1 - 10.
Homo sapiens
Gene: ... gene. Biological context of MEN1 All tumours with MEN1 gene mutation showed LOH on 11q13, making...Disease relevance of MEN1 MEN1( Menin) gene- disease database Some cases are caused by inherited syndromes, such as multiple endocrine neoplasia type 1( MEN1; ref. 2 ). In most cases, the molecular basis...
Mus musculus
Gene: ... Disease relevance of Men1 Gene expression profiling in insulinomas of Men1{ beta }- cell mutant... loss of both copies of Men1, implies that additional somatic events are required for adenoma formation in beta cells. Conditional homozygous inactivation of the Men1 gene in the pituitary gland and endocrine...
MeSH term: ... identity( 50 %) with the extended- spectrum class A beta- lactamase MEN- 1 from E. coli. A patient had... neoplasia- type 1( MEN1) is an autosomal dominant familial cancer syndrome characterized by tumors... hyperparathyroidism segregating a missense MEN1 mutation and showing loss of the wild- type alleles in the parathyroid... / Synonyms: MEN 1; MEN1
Rattus norvegicus
Gene: ... Disease relevance of Men1 We here characterize the MEN1 gene homologs of the mouse and rat. cDNA was isolated from a mouse phage library, and two alternative MEN1 mRNA transcripts containing variant 5... information on Men1 Germ- line missense mutations of the receptor- like tyrosine kinase ret are the causative...
MeSH term: ... on chromosome 11, which may also involve the MEN- 1 gene. We have recently shown that 70% of human...) for polymorphic markers on 11q13, the site of the MEN1 tumour suppressor gene. Here, we show that loss... tumours with MEN1 gene mutation showed LOH on 11q13, making the tumour cells hemi- or homozygous...
Homo sapiens
Gene: ... in the human CDKN1B gene in a MEN1 mutation- negative patient presenting with pituitary and parathyroid tumors... to regulatory polymorphisms could indeed influence the risk of childhood pre- B ALL and contribute... / Synonyms: MEN1B
MeSH term: ... sporadic adenomas from patients without MEN- 1, 9 showed similar allelic losses in chromosome 11; in 7 the losses included the apparent MEN- 1 locus. A reduction in the DNA methyltransferase activity in Min mice... was observed in three cases, and CRH receptor signal was undetected in all. METHODS: The expression...
MeSH term: ... cascade. Multiple endocrine neoplasia type 1( MEN- 1) is a predisposition to hyperplasia...
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Steven Johnsen and Donald R. Forsdyke and Kehinde Ross and Andrew Perry and Jonathan Eisen and A. Shimabukuro-Vornhagen and Giuseppe Rotondo and Gordon Laurie and Berkley Lynch and Kung-Hao Liang and Matthias Gstaiger and Thomas Pfeiffer and Marta Ramirez and Grant MacGregor and Jingyu Li and Fedik Rahimov and M El Gizouli and Marta Ramirez Gaite and Oswaldo Ribeiro-filho and Ralf Weigel and Bjoern Hamberger and Alexander Kanitz and Andreas Zankl and Chunming Ding and Maruf Yunus and Jonathan S. Berg and Michael Cariaso and Zakir Thomas and Monique Timberlake-Brady and LC Dore and Nan Shen and R. Eric Collins and Kuang-Mao Chiang and Brendan McMahon and John Chew and Wen-Ming Yang and Robert Hoffmann and J.B. Stewart and Manuela Cucerea and Ignacio García and William James and Thomas Kelder and Gregory Melahn and YINGDE ZHU and Andres Muro and Gabriel Santpere and Jeff Freilich and Junbin Qian and Steffen Poulsen and Eric Villard and Rafael Sidi and Grant Cramer and Chris Sander and Alexandre Chigaev and Florian Uhle and Carl Fulp and Andrew Brown and Xiaozhu Zhou and Corina Dutu and Hilary Spencer and david germano and Abbas Dehghan and Eung-ju PARK and Chris Sander and Albert Vilella and Miao Tian and Anjali Bheda and Michael Nevels and Jun Liu and D Delano and Chitose Taya and Soomi Cheong and David Kavanagh and Maha Karnoub and Hilmar Lapp and Christian Pallasch and Daniel Mietchen and Biju Balakrishnan and Keith Ashman and Juan Carlos Sobrino and Anshu Bhardwaj and Grzegorz Wickiel and Matthew Day and Anthony Sebastian and Vedran Katavic and Liang Long and Barry Wanner and Sarah Snelling and Fernando Montanes and Omobosede Fashedemi and Gustavo Cervantes and Manoj Kumar and Edward D Great and Paul Paukstelis and Roy Soetikno and Ana I Caño-Delgado and Minsoo Choi and Lei Wang and Brenda Riley and A Michelle Moon and Jon Moulton and Mahmoud Elshahawy and Meagan Gillespie and Banundari Rachmawati and Qian Han and Eric Danner and Xavier Fouillet and Madhusudhan Acharya and Brian Young and Chandra Sekhar Mukhopadhyay and shrawan bhattacharjee and Marieke van der Linden and cj hoban and Sandi Pniauskas and jackie gao and Metin Bilgin and Gillian L. Dalgliesh and Karl Wotton and Iveta Herichova and Yuji Morita and Marta Hernandez and Gregor Krings and Marco Briones and Tim D. Smith and Yiumo Michael Chan and Zhenyu Guo and Barry Barclay and Hong Wang and tarali chowdhury and Tilman Brummer and Nuno Faria and Tamir Ben David and Myles Axton and Yannick Fonseca and Francis Castets and Modesto Redrejo-Rodríguez and Bruce Herron and Toshio Fujita and Elena Puccetti and Zhang Zhang and John Osborne and Illes J Farkas and Fernando Andres and Phyllis Pugh and Jonathan Court and Tim Vickers and Nir Friedman and Holger Dick and Ya-Chen Liang and Jonathan Froehlich and Haitham Sobhy and David Abraham and Stephane Krief and Yaroslav Nikolaev and Qiping Feng and d gupta and R Thapar and Susan Wee and Michael Rehman and SOUMITRA GHOSH and Mohamed Eweida and Cedric Uytingco and Nie hongchuan and David Steenblock and Mark A. Kukucka and Zoli Fekete and Sergei Kozlov and Javier Jara and Osama Naguib and Felix Benninger and jean-marc lo-guidice and VASUDEVA BHAT and Anne O. Summers and Bjoern Titz and Anna Levine and Klas Udekwu and Robert Hoffmann