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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 177 documents. Results 1 - 10.

Homo sapiens
Gene: ... to appear and colocalize with MSH4. Regulatory relationships of MLH1 MSH2 was expressed in all stages...Disease relevance of MLH1 The MLH1 D132H variant is associated with susceptibility to sporadic colorectal cancer. We assessed the prevalence of MSH2 and MLH1 mutations in families suspected of having... / Synonyms: DNA mismatch repair protein Mlh1; hMLH1
Saccharomyces cerevisiae S288c
Gene: ... functions in mitosis and meiosis, and they suggest that some, but not all, MLH1 mutations may be a source...Disease relevance of MLH1 Inherited mutations in the mismatch repair( MMR) genes MSH2 and MLH1... in the DNA mismatch repair( MMR) gene MLH1 are associated with a large percentage of hereditary non... / Synonyms: DNA mismatch repair protein MLH1
Mus musculus
Gene: ... Disease relevance of Mlh1 The findings may provide a basis for understanding the greater predisposition to intestinal cancer of Mlh1 (-/-) mice. We showed that mice heterozygous and homozygous for the Mlh1 gene are predisposed to developing tumors of the gastrointestinal( GI) tract, lymphomas... / Synonyms: DNA mismatch repair protein Mlh1
Arabidopsis thaliana
Gene: ... of the E. coli MutL gene, which we have called AtMLH1 for Arabidopsis thaliana MutL- homologue 1. High... Holliday junctions( dHjs) are formed, but the MutL homologue AtMLH1, which forms a heterocomplex with At... of the AtMLH1 gene was isolated. Sequence analysis revealed that the product of this gene shows extensive...
Gallus gallus
Gene: ... High impact information on MLH1 Distribution of MLH1 foci on the synaptonemal complexes of chicken oocytes. The frequency and distribution of the mismatch repair protein MLH1 was analyzed on synaptonemal complex spreads of chicken oocytes using indirect immunofluorescence. It is concluded that MLH1 foci...
MeSH term: ... Reaction Furthermore, PCR amplification of hMLH1 cDNA from mRNA from a HNPCC patient, followed by in vivo... mutation in hMLH1 using this method. METHODS: The requisition form used by the PCR testing service included... by neutralization in five donors( 0. 001 percent of all donations tested ), all of whom were also positive for HIV...
Solanum lycopersicum
Gene
Caenorhabditis elegans
Gene
MeSH term: ... inhibited tumorigenicity in a wild- type RAS- dependent manner. Because MLH1, MSH2 and MSH6 mutations... ectopically activated in colon cancer. Inherited mutations in the mismatch repair( MMR) genes MSH2 and MLH1... colon cancer cases, while hereditary- non polyposis colon cancer( HNPCC) may cause five percent of all...
MeSH term: ... in the kindred were independent predictors of germ- line mutations of MSH2 or MLH1. Mice homozygous... suggest that it is more protective against colorectal cancer, possibly via butyrate. The MLH1 D132H...

 

 
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