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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Your search matched a total of 24 documents. Results 1 - 10.

Drosophila melanogaster
Gene: ... High impact information on MRG15 These analyses also suggest that the msl- 3/ MRG15 duplication... together suggest that the MRG15 chromo domain may function as an adaptor module which can bind to a modified histone H3 in a mode different from that of the HP1/ Pc chromo domains. The MRG15 chromo domain... / Synonyms: DmMRG15; Mrg15; Protein MRG15
Mus musculus
Gene: ... Disease relevance of Morf4l1 We determined by chromatin immunoprecipitation that MRG15... effect by the evolutionarily conserved MRG15 protein but not vice versa. MRG15 regulates embryonic development and cell proliferation. Cell proliferation defects are also observed in Mrg15 -/- mouse embryonic... / Synonyms: MRG15; Mrg15; Transcription factor-like protein MRG15
Rattus norvegicus
Homo sapiens
Gene: ... Disease relevance of MORF4L1 The C- terminal part of MRG15 forms a conserved MRG domain which..., possibly due to competition with hMRG15 in endogenous nucleoprotein complexes. High impact information on MORF4L1 MRG15, a closely related family member, is in a complex with the retinoblastoma tumor... / Synonyms: MRG15; Transcription factor-like protein MRG15
Chemical compound: ... days( I- HL- 60). We determined by chromatin immunoprecipitation that MRG15 was recruited to the alpha...
Caenorhabditis elegans
Gene: ... High impact information on Y37D8A. 11 To determine the biological functions of human MRG15( hMRG15) we used RNA- mediated interference( RNAi) to silence mrg- 1, the Caenorhabditis elegans ortholog, and its closest homolog Y37D8A. 11....
MeSH term: ... Disease relevance of Chromatin Immunoprecipitation Here, we combine chromatin immunoprecipitation and high- density oligonucleotide microarrays to define the in vivo DNA targets of the LexA transcriptional repressor in Escherichia coli. We determined by chromatin immunoprecipitation that MRG15 was recruited...
Homo sapiens
Gene: ... in the regulation of gene expression and genome organisation. MRG15, a novel chromodomain protein, is present in two...
Homo sapiens
Gene: ... Disease relevance of PALB2 The PALB2 1592delT mutation has a strong effect on familial breast cancer risk. Physical interactions of PALB2 Although damage- induced RAD51 foci formation and mitomycin C sensitivity appeared normal in MRG15- binding defective PALB2 mutants, these cells exhibited a significant...
Homo sapiens
Gene: ... Disease relevance of MRFAP1 The C- terminal part of MRG15 forms a conserved MRG domain which... and as early as 7 days during embryonic development. Collectively these results suggest that MRG15 regulates..., and reveal insights into the potential biological function of MRG15 in transcription regulation and chromatin...


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