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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 62 documents. Results 1 - 10.

Mus musculus
Gene: ... Disease relevance of Nfatc1 These defects lead to embryonic death at E14. 5 and are similar to those observed in other mouse models of congenital heart disease, including Sox4 and Nfatc1 null embryos... that NFATc1 represents a potential therapeutic target for bone disease and reveals a mechanism that underlies... / Synonyms: NFATc1
Homo sapiens
Gene: ... Disease relevance of NFATC1 We propose that the MCP- 1- induced TRAP (+)/ CTR (+) multinuclear cells represent an arrested stage in osteoclast differentiation, after NFATc1 induction and cellular... factor NFATc1 fail to form pulmonary and aortic valves, a defect reminiscent of some types of congenital... / Synonyms: NFATc1
MeSH term: ... activity have not been elucidated. Among NFAT proteins, NFATc1 is crucial for the differentiation of bone... mutations have all contributed to increased understanding of the skeletal effects of estrogen, both in males...
MeSH term: ... and Osterix cooperatively regulate bone formation. In fact, bone formation is inhibited in Nfatc1- and Nfatc2...
MeSH term: ... disease, including Sox4 and Nfatc1 null embryos. Congenital heart disease reminiscent of partial trisomy 2... vessel disease, cardiac autonomic neuropathy, and insulin resistance may all contribute...
MeSH term: ... inoculated subcutaneously. Biological context of Bone Diseases Thus, this study establishes that NFATc1... the essential role of NFATc1 in bone homeostasis. Bisphosphonates, drugs used widely in the treatment of bone... to low normal values in all 14 patients, accompanied by a decrease in urine calcium and hydroxyproline...
MeSH term: ... endocardial Nfatc1 expression within developing cardiac valves. High TGF beta- 1 RNA levels continue... valves and septa. Nfatc1 is an endocardial transcription factor required for development of cardiac...
Chemical compound: ... uptake of NFATc1 was 4. 6 times lower in resting fibers exposed to leptomycin B than during electrical...

 

 
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