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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 76 documents. Results 1 - 10.

Homo sapiens
Gene: ... Disease relevance of OGG1 One class utilizes an internal Lys residue as the active site nucleophile, and includes Escherichia coli Nth and both known mammalian DNA glycosylase/ AP lyases, namely, OGG1 and NTH1. RESULTS: Polymorphism OGG1 S326C was associated with an increased risk of colorectal cancer[ odds ratio...
Saccharomyces cerevisiae S288c
Gene: ... Disease relevance of OGG1 No significant acceleration was observed in the repair of either a single...- oxoguanine, initiated by the bifunctional glycosylase OGG1. High impact information on OGG1 In S. cerevisiae... in OGG1, which encodes a MutM homolog, resulting in a 140- to 218- fold increase in the G: C- to- T...
Drosophila melanogaster
Gene: ... Disease relevance of Ogg1 Cleavage of 8- OH- Gua. C duplex involves the formation of a reaction intermediate that is converted into a stable covalent adduct in the presence of sodium borohydre. dOgg1 complements the mutator phenotype of fpg mutY mutants of Escherichia coli. High impact information on Ogg1... / Synonyms: dOGG1; dOgg1
Arabidopsis thaliana
Gene: ... Disease relevance of OGG1 Furthermore, expression of AtOGG1 in an Escherichia coli strain that is deficient in the repair of 8- oxoG in DNA suppresses its spontaneous- mutator phenotype....
Mus musculus
Gene: ... Disease relevance of Ogg1 Here, we demonstrate that deficiencies in Myh and Ogg1 predispose 65. 7.../ carcinoma spontaneously developed in Ogg1 knockout mice approximately 1. 5 years after birth in which 8- oxoG was found to accumulate in their genomes. The rate of developing malignant tumors in Ogg1 knockout mice...
Rattus norvegicus
Gene: ... Disease relevance of Ogg1 Acetoaminophen- induced accumulation of 8- oxodeoxyguanosine through reduction of Ogg1 DNA repair enzyme in C6 glioma cells. High impact information on Ogg1 Rat 7, 8- dihydro- 8.... In addition, there was no indication of increased oxidative stress in mitochondria from Ogg1 -/- mice...
MeSH term: ... . The activity of Ogg1 was not significantly different in the CB; however, in the CP of ICR mice, the activity of Ogg1 was 34% and 31% lower than Balb/ c and C57BL/ J, respectively. Pretreatment with compound 48/ 80...
Dictyostelium discoideum AX4
Gene
Macaca mulatta
Gene
Pan troglodytes
Gene

 

 
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