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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 304 documents. Results 1 - 10.

Homo sapiens
Gene: ... Disease relevance of RAD51 Structural and mutational results characterize RAD51 interactions... role for the WRN RecQ helicase protein in RAD51- dependent HR and identify a mechanistic link between..., and genetic instability in human somatic cells. RAD51 status did not affect ovarian cancer risk. Inferring... / Synonyms: DNA repair protein RAD51 homolog 1; HsRAD51; HsRad51
Saccharomyces cerevisiae S288c
Gene: ... recombination pathway. Chemical compound and disease context of RAD51 Remarkably, the mutant cell lines all...Disease relevance of RAD51 Dmc1 and Rad51, yeast homologs of the E. coli RecA protein, are shown... cells with 100 nM of RAD51 antisense ODNs significantly enhanced the radiation- induced cell kill... / Synonyms: DNA repair protein RAD51
Mus musculus
Gene: ... Disease relevance of Rad51 The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross- linking agent cisplatin. METHODS: To enhance the anti- cancer effect of chemotherapy, we transferred siRNA against Rad51 into various human... / Synonyms: DNA repair protein RAD51 homolog 1; RAD51 homolog A; Rad51a
Homo sapiens
Gene: ... that RAD51C and S6K were consistently expressed in all cases in which they were amplified and also in some...High impact information on RAD51C In addition to being critical for RAD51 focus formation, RAD51C localizes to DNA damage sites. Inhibition of RAD51C results in a decrease in cellular proliferation... / Synonyms: DNA repair protein RAD51 homolog 3; RAD51 homolog C; RAD51-like protein 2
Mus musculus
Gene: ... High impact information on Rad51l1 The new genes( R51H2 and R51H3) were mapped to human chromosomes... occurs at elevated levels in the testis compared with other tissues. A key player in HR is Xrcc2, a Rad51- like protein. Biological context of Rad51l1 Xrcc2 is one of a family of five Rad51- like genes... / Synonyms: DNA repair protein RAD51 homolog 2; RAD51-like protein 1; Rad51l1
Homo sapiens
Gene: ... Disease relevance of RAD51AP1 The Pir51 protein was expressed in Escherichia coli and purified...- and RAD51- associated homologous recombination in response to DNA damage. Pir51, a Rad51- interacting... chromosomal breaks. Pir51, a protein of unknown function that interacts with Rad51, was identified in a screen... / Synonyms: RAD51-associated protein 1; RAD51-interacting protein
Homo sapiens
Gene: ... Disease relevance of RAD51L1 Among them, Rad51B is unique in that the gene maps to the human... particularly in uterine leiomyomas. Here, we show that haploinsufficiency of RAD51B causes mild hypersensitivity to DNA- damaging agents, a mild reduction in sister chromatid exchange, impaired Rad51 focus... / Synonyms: DNA repair protein RAD51 homolog 2; RAD51 homolog B; RAD51-like protein 1
Homo sapiens
Gene: ... Disease relevance of RAD51L3 The variant E233G of the RAD51D gene could be a low- penetrance allele... different inactivating germline mutations in the RAD51D gene were found to be associated with significantly( 6 fold) increased risk of ovarian cancer. High impact information on RAD51L3 Telomere maintenance... / Synonyms: DNA repair protein RAD51 homolog 4; RAD51 homolog D; RAD51-like protein 3
Mus musculus
Gene: ... High impact information on Rad51ap1 We have used the yeast two- hybrid system to clone murine cDNA sequences that encode two RAD51- associated molecules, RAB22 and RAB163. This localization was confirmed... of several genes such as Per3 and Rad51ap1 displayed inter- strain differences.... / Synonyms: RAD51-associated protein 1; RAD51-interacting protein
Mus musculus
Gene: ... High impact information on Rad51l3 The Rad51d -/- Trp53 -/- mouse embryo- derived fibroblasts were... chromosomal instability in Rad51d- deficient mouse cells. Spontaneous frequencies of sister chromatid exchange were not affected by the absence of Rad51d, but sister chromatid exchange frequencies did fail... / Synonyms: DNA repair protein RAD51 homolog 4; RAD51-like protein 3; Rad51l3

 

 
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