Gene Review:
Rad51 - RAD51 homolog
Mus musculus
Synonyms:
AV304093, DNA repair protein RAD51 homolog 1, RAD51 homolog A, Rad51a, Reca
- The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross-linking agent cisplatin. Bhattacharyya, A., Ear, U.S., Koller, B.H., Weichselbaum, R.R., Bishop, D.K. J. Biol. Chem. (2000)
- Rad51 siRNA delivered by HVJ envelope vector enhances the anti-cancer effect of cisplatin. Ito, M., Yamamoto, S., Nimura, K., Hiraoka, K., Tamai, K., Kaneda, Y. The journal of gene medicine. (2005)
- IRS-1-Rad51 nuclear interaction sensitizes JCV T-antigen positive medulloblastoma cells to genotoxic treatment. Trojanek, J., Ho, T., Croul, S., Wang, J.Y., Chintapalli, J., Koptyra, M., Giordano, A., Khalili, K., Reiss, K. Int. J. Cancer (2006)
- Genomic instability in laminopathy-based premature aging. Liu, B., Wang, J., Chan, K.M., Tjia, W.M., Deng, W., Guan, X., Huang, J.D., Li, K.M., Chau, P.Y., Chen, D.J., Pei, D., Pendas, A.M., Cadiñanos, J., López-Otín, C., Tse, H.F., Hutchison, C., Chen, J., Cao, Y., Cheah, K.S., Tryggvason, K., Zhou, Z. Nat. Med. (2005)
- Inactivation of Cdc7 kinase in mouse ES cells results in S-phase arrest and p53-dependent cell death. Kim, J.M., Nakao, K., Nakamura, K., Saito, I., Katsuki, M., Arai, K., Masai, H. EMBO J. (2002)
- Distribution of the Rad51 recombinase in human and mouse spermatocytes. Barlow, A.L., Benson, F.E., West, S.C., Hultén, M.A. EMBO J. (1997)
- RecA-like proteins are components of early meiotic nodules in lily. Anderson, L.K., Offenberg, H.H., Verkuijlen, W.M., Heyting, C. Proc. Natl. Acad. Sci. U.S.A. (1997)
- A mouse model for the molecular characterization of brca1-associated ovarian carcinoma. Xing, D., Orsulic, S. Cancer Res. (2006)
- Overexpression of mammalian Rad51 does not stimulate tumorigenesis while a dominant-negative Rad51 affects centrosome fragmentation, ploidy and stimulates tumorigenesis, in p53-defective CHO cells. Bertrand, P., Lambert, S., Joubert, C., Lopez, B.S. Oncogene (2003)
- Nuclear Rad51 foci induced by DNA damage are distinct from Rad51 foci associated with B cell activation and recombination. Li, M.J., Maizels, N. Exp. Cell Res. (1997)
- Rad51 immunocytology in rat and mouse spermatocytes and oocytes. Moens, P.B., Chen, D.J., Shen, Z., Kolas, N., Tarsounas, M., Heng, H.H., Spyropoulos, B. Chromosoma (1997)
- Deregulation of homologous recombination DNA repair in alkylating agent-treated stem cell clones: a possible role in the aetiology of chemotherapy-induced leukaemia. Worrillow, L.J., Allan, J.M. Oncogene (2006)
- Mechanisms of enhanced radiation response following epidermal growth factor receptor signaling inhibition by erlotinib (Tarceva). Chinnaiyan, P., Huang, S., Vallabhaneni, G., Armstrong, E., Varambally, S., Tomlins, S.A., Chinnaiyan, A.M., Harari, P.M. Cancer Res. (2005)
- Analysis of mouse Rad54 expression and its implications for homologous recombination. Essers, J., Hendriks, R.W., Wesoly, J., Beerens, C.E., Smit, B., Hoeijmakers, J.H., Wyman, C., Dronkert, M.L., Kanaar, R. DNA Repair (Amst.) (2002)
- Elevated expression of exogenous Rad51 leads to identical increases in gene-targeting frequency in murine embryonic stem (ES) cells with both functional and dysfunctional p53 genes. Domínguez-Bendala, J., Priddle, H., Clarke, A., McWhir, J. Exp. Cell Res. (2003)
- The Hop2 and Mnd1 proteins act in concert with Rad51 and Dmc1 in meiotic recombination. Petukhova, G.V., Pezza, R.J., Vanevski, F., Ploquin, M., Masson, J.Y., Camerini-Otero, R.D. Nat. Struct. Mol. Biol. (2005)
- Impaired meiotic DNA-damage repair and lack of crossing-over during spermatogenesis in BRCA1 full-length isoform deficient mice. Xu, X., Aprelikova, O., Moens, P., Deng, C.X., Furth, P.A. Development (2003)
- Homozygous germ line mutation in exon 27 of murine Brca2 disrupts the Fancd2-Brca2 pathway in the homologous recombination-mediated DNA interstrand cross-links' repair but does not affect meiosis. Atanassov, B.S., Barrett, J.C., Davis, B.J. Genes Chromosomes Cancer (2005)
- Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development. Ajioka, I., Maeda, T., Nakajima, K. Eur. J. Neurosci. (2006)