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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Your search matched a total of 189 documents. Results 1 - 10.

Mus musculus
Gene: ... of the matrilin- 1 gene. Co- localisations of Sox9 Expression of Col2a1 colocalized with expression of Sox9 in all...Disease relevance of Sox9 Hypoxia induces chondrocyte- specific gene expression in mesenchymal cells in association with transcriptional activation of Sox9. L- Sox5, Sox6, and Sox9 were coexpressed... / Synonyms: Sox-9; Transcription factor SOX-9
Homo sapiens
Gene: ... Disease relevance of SOX9 In humans, mutations in the gene for SOX9, a transcription factor... of SF1, WT1 and SOX9 is responsible for 46, XY gonadal dysgenesis. We have screened seven CD patients... for mutations in the entire open reading frame of SOX9. Ectopic expression of full- length SOX9 or its RUNX2... / Synonyms: Transcription factor SOX-9
Rattus norvegicus
Gene: ... High impact information on Sox9 Transfection experiments in culture systems revealed that cGKII attenuated the Sox9 functions to induce the chondrogenic differentiation and to inhibit the hypertrophic... by the silencing of Sox9 through RNA interference. Inhibition of the protein kinase C alpha and NFkappaB pathways...
Xenopus laevis
Gene: ... Disease relevance of SOX9 By whole- mount in situ hybridization, Sox9 was first detected at stage... of the liver diverticulum. Noggin overexpression by recombinant adenovirus infection reduced Sox9, patched, Ihh... to differentiate into chondrocyte lineage by culturing in differentiation medium. High impact information on SOX9... / Synonyms: sox-9; sox9
Pan troglodytes
Gene: ... High impact information on SOX9 DAX1 and SRY have been added to the X and Y chromosomes, respectively, during mammalian evolution, whereas SOX9 remains autosomal....
Canis lupus familiaris
Gene: ... Disease relevance of SOX9 Thus a mutation in the coding sequence as well as the promoter region of the SOX9 gene might be excluded as a cause of this type of intersexuality. High impact information on SOX9 Further, manipulation of the mouse collagen type XI( mColXI) promoter by the incorporation of SOX9...
MeSH term: ... in an effort to understand the likely sites of estrogen action. Gene context of Testis SOX9 encodes a putative... tissues, and in fetal testis and skeletal tissue. Here, we show that Sox9 is sufficient to induce testis... into the scrotum in males and blockade of vagina opening in females. Dax1 is required for testis determination. Sox...
Danio rerio
Gene: ... and sox9a, also completely eliminates all indications of otic cells. Twelve cell lines were established...Disease relevance of sox9a Enzymatically dissociated testicular cells containing germ cells were co... of Sertoli cells such as phagocytic activity and transcription of the Wilms' tumor suppressor wt1 and sox9a...
Sus scrofa
Gene: ... High impact information on SOX- 9 In vitro expression studies performed in CV- 1 cells demonstrated that pig SOX9 cDNA transactivated the pig SRY promoter but that pig SRY cDNA did not. Gel retardation assays using this binding site showed specific binding to SOX9- enriched nuclear extracts...
Gallus gallus
Gene: ... High impact information on SOX9 Here, we show that in Xenopus, Sox8 accumulates at the lateral... expression precedes that of Sox9 and Sox10 in neural crest progenitors. By misexpressing SOX9 in the mesoderm of the gizzard, we show that SOX9 is able to transdifferentiate the adjacent gizzard epithelium into pyloric...


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