Your search matched a total of 207 documents. Results 1 - 10.
Homo sapiens
Gene: ... Disease relevance of TOP1 The t( 11; 20 )( p15; q11) chromosomal translocation associated with therapy- related myelodysplastic syndrome results in an NUP98- TOP1 fusion. Moreover, in a murine bone marrow transplantation model, NUP98- TOP1 expression led to a lethal, transplantable leukemia...
Homo sapiens
Gene: ... High impact information on TOP1MT The TOP1mt gene is highly homologous to the nuclear TOP1 gene and consists of 14 exons.... / Synonyms: TOP1mt
Arabidopsis thaliana
Gene: ... High impact information on TOP1alpha The top1 nucleotide sequence encoded an open reading frame of 2370 bp, predicting a protein of 90 kDa. Evaluation of the top1 mRNA steady- state level revealed... proliferation. Despite the physiological importance, the regulation of top1 gene expression has not yet been... / Synonyms: TOP1; TOP1ALPHA
Mus musculus
Gene: ... Disease relevance of Top1 OBJECTIVE: Autoantibodies to DNA topoisomerase I( topo I) are associated...- sensitive cells( Deffie et al ., Cancer Res ., 49: 58- 62, 1989). High impact information on Top1 DNA... embryos lacking DNA topoisomerase IIbeta. Chemical compound and disease context of Top1 Decreased DNA... / Synonyms: Top-1
Arabidopsis thaliana
Gene: ... High impact information on TOP1BETA Disruption of a DNA topoisomerase I gene affects morphogenesis in Arabidopsis. RHL1 is an essential component of the plant DNA topoisomerase VI complex and is required for ploidy- dependent cell growth. DNA gyrase is the bacterial DNA topoisomerase( topo) that supercoils DNA... / Synonyms: TOP1; TOP1BETA
Drosophila melanogaster
Gene: ... Disease relevance of Top1 Using a single- molecule micromanipulation setup, we follow the real... information on Top1 The in vivo distribution of topoisomerase I on specific DNA sequences is determined.... Biological context of Top1 This enzyme partially relaxes a hypernegatively supercoiled plasmid substrate... / Synonyms: TOP1; l(1)top1; top1
Schizosaccharomyces pombe 972h-
Gene: ... High impact information on top1 In contrast, the double top1 top2 mutants were rapidly arrested at various stages of the cell cycle, showing a strikingly altered nuclear chromatin region....
Saccharomyces cerevisiae S288c
Gene: ... interactions of TOP1 None of these genes is required for viability and all SLX null mutations are synthetically...Disease relevance of TOP1 Rabbit antibodies specific to yeast DNA topoisomerase I were used... have investigated the role of TOP1 in hydrogen peroxide toxicity. We have shown that overexpression...
Homo sapiens
Gene: ... High impact information on TOP1P2 A TaqI RFLP at the human TOP1 pseudogene locus on chromosome 22q11. 2- 13. 1( TOP1P2). The Top- 1ps locus, together with the immunoglobulin- lambda- light- chain... of the human pseudogene TOP1P2. Increased loss of heterozygosity during tumor progression or recurrence...
Rattus norvegicus
Gene: ... Disease relevance of Top1 Newly replicated DNA is associated with DNA topoisomerase II in cultured.... High impact information on Top1 Our results suggest that DNA topoisomerase II may interact with newly.... Biological context of Top1 We have now examined whether the enzyme, DNA topoisomerase II, which has been...
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Steven Johnsen and Donald R. Forsdyke and Kehinde Ross and Andrew Perry and Jonathan Eisen and A. Shimabukuro-Vornhagen and Giuseppe Rotondo and Gordon Laurie and Berkley Lynch and Kung-Hao Liang and Matthias Gstaiger and Thomas Pfeiffer and Marta Ramirez and Grant MacGregor and Jingyu Li and Fedik Rahimov and M El Gizouli and Marta Ramirez Gaite and Oswaldo Ribeiro-filho and Ralf Weigel and Bjoern Hamberger and Alexander Kanitz and Andreas Zankl and Chunming Ding and Maruf Yunus and Jonathan S. Berg and Michael Cariaso and Zakir Thomas and Monique Timberlake-Brady and LC Dore and Nan Shen and R. Eric Collins and Kuang-Mao Chiang and Brendan McMahon and John Chew and Wen-Ming Yang and Robert Hoffmann and J.B. Stewart and Manuela Cucerea and Ignacio García and William James and Thomas Kelder and Gregory Melahn and YINGDE ZHU and Andres Muro and Gabriel Santpere and Jeff Freilich and Junbin Qian and Steffen Poulsen and Eric Villard and Rafael Sidi and Grant Cramer and Chris Sander and Alexandre Chigaev and Florian Uhle and Carl Fulp and Andrew Brown and Xiaozhu Zhou and Corina Dutu and Hilary Spencer and david germano and Abbas Dehghan and Eung-ju PARK and Chris Sander and Albert Vilella and Miao Tian and Anjali Bheda and Michael Nevels and Jun Liu and D Delano and Chitose Taya and Soomi Cheong and David Kavanagh and Maha Karnoub and Hilmar Lapp and Christian Pallasch and Daniel Mietchen and Biju Balakrishnan and Keith Ashman and Juan Carlos Sobrino and Anshu Bhardwaj and Grzegorz Wickiel and Matthew Day and Anthony Sebastian and Vedran Katavic and Liang Long and Barry Wanner and Sarah Snelling and Fernando Montanes and Omobosede Fashedemi and Gustavo Cervantes and Manoj Kumar and Edward D Great and Paul Paukstelis and Roy Soetikno and Ana I Caño-Delgado and Minsoo Choi and Lei Wang and Brenda Riley and A Michelle Moon and Jon Moulton and Mahmoud Elshahawy and Meagan Gillespie and Banundari Rachmawati and Qian Han and Eric Danner and Xavier Fouillet and Madhusudhan Acharya and Brian Young and Chandra Sekhar Mukhopadhyay and shrawan bhattacharjee and Marieke van der Linden and cj hoban and Sandi Pniauskas and jackie gao and Metin Bilgin and Gillian L. Dalgliesh and Karl Wotton and Iveta Herichova and Yuji Morita and Marta Hernandez and Gregor Krings and Marco Briones and Tim D. Smith and Yiumo Michael Chan and Zhenyu Guo and Barry Barclay and Hong Wang and tarali chowdhury and Tilman Brummer and Nuno Faria and Tamir Ben David and Myles Axton and Yannick Fonseca and Francis Castets and Modesto Redrejo-Rodríguez and Bruce Herron and Toshio Fujita and Elena Puccetti and Zhang Zhang and John Osborne and Illes J Farkas and Fernando Andres and Phyllis Pugh and Jonathan Court and Tim Vickers and Nir Friedman and Holger Dick and Ya-Chen Liang and Jonathan Froehlich and Haitham Sobhy and David Abraham and Stephane Krief and Yaroslav Nikolaev and Qiping Feng and d gupta and R Thapar and Susan Wee and Michael Rehman and SOUMITRA GHOSH and Mohamed Eweida and Cedric Uytingco and Nie hongchuan and David Steenblock and Mark A. Kukucka and Zoli Fekete and Sergei Kozlov and Javier Jara and Osama Naguib and Felix Benninger and jean-marc lo-guidice and VASUDEVA BHAT and Anne O. Summers and Bjoern Titz and Anna Levine and Klas Udekwu and Robert Hoffmann