Gene Review:
TOP1 - DNA topoisomerase 1
Saccharomyces cerevisiae S288c
Synonyms:
DNA topoisomerase I, MAK1, MAK17, Maintenance of killer protein 1, YOL006C
- Cloning of yeast TOP1, the gene encoding DNA topoisomerase I, and construction of mutants defective in both DNA topoisomerase I and DNA topoisomerase II. Goto, T., Wang, J.C. Proc. Natl. Acad. Sci. U.S.A. (1985)
- Hydrogen peroxide induces topoisomerase I-mediated DNA damage and cell death. Daroui, P., Desai, S.D., Li, T.K., Liu, A.A., Liu, L.F. J. Biol. Chem. (2004)
- Overexpression of type I topoisomerases sensitizes yeast cells to DNA damage. Nitiss, J.L., Nitiss, K.C., Rose, A., Waltman, J.L. J. Biol. Chem. (2001)
- Identification of a vaccinia virus gene encoding a type I DNA topoisomerase. Shuman, S., Moss, B. Proc. Natl. Acad. Sci. U.S.A. (1987)
- Platinated DNA adducts enhance poisoning of DNA topoisomerase I by camptothecin. van Waardenburg, R.C., de Jong, L.A., van Eijndhoven, M.A., Verseyden, C., Pluim, D., Jansen, L.E., Bjornsti, M.A., Schellens, J.H. J. Biol. Chem. (2004)
- A subthreshold level of DNA topoisomerases leads to the excision of yeast rDNA as extrachromosomal rings. Kim, R.A., Wang, J.C. Cell (1989)
- Both DNA topoisomerases I and II relax 2 micron plasmid DNA in living yeast cells. Saavedra, R.A., Huberman, J.A. Cell (1986)
- Need for DNA topoisomerase activity as a swivel for DNA replication for transcription of ribosomal RNA. Brill, S.J., DiNardo, S., Voelkel-Meiman, K., Sternglanz, R. Nature (1987)
- Mitotic chromosome condensation in the rDNA requires TRF4 and DNA topoisomerase I in Saccharomyces cerevisiae. Castaño, I.B., Brzoska, P.M., Sadoff, B.U., Chen, H., Christman, M.F. Genes Dev. (1996)
- Peptide sequencing and site-directed mutagenesis identify tyrosine-727 as the active site tyrosine of Saccharomyces cerevisiae DNA topoisomerase I. Lynn, R.M., Bjornsti, M.A., Caron, P.R., Wang, J.C. Proc. Natl. Acad. Sci. U.S.A. (1989)
- SCT1 mutants suppress the camptothecin sensitivity of yeast cells expressing wild-type DNA topoisomerase I. Kauh, E.A., Bjornsti, M.A. Proc. Natl. Acad. Sci. U.S.A. (1995)
- Mitotic recombination in the rDNA of S. cerevisiae is suppressed by the combined action of DNA topoisomerases I and II. Christman, M.F., Dietrich, F.S., Fink, G.R. Cell (1988)
- Tyrosyl-DNA phosphodiesterase (Tdp1) participates in the repair of Top2-mediated DNA damage. Nitiss, K.C., Malik, M., He, X., White, S.W., Nitiss, J.L. Proc. Natl. Acad. Sci. U.S.A. (2006)
- On the relationship of the ATP-independent, mitochondrial associated DNA topoisomerase of Saccharomyces cerevisiae to the nuclear topoisomerase I. Wang, J., Kearney, K., Derby, M., Wernette, C.M. Biochem. Biophys. Res. Commun. (1995)
- Purification and functional characterization of type II DNA topoisomerase from rat testis and comparison with topoisomerase II from liver. Galande, S., Muniyappa, K. Biochim. Biophys. Acta (1996)
- Plasmid linking number change induced by topoisomerase I-mediated DNA damage. Duann, P., Sun, M., Lin, C.T., Zhang, H., Liu, L.F. Nucleic Acids Res. (1999)
- HPR1, a novel yeast gene that prevents intrachromosomal excision recombination, shows carboxy-terminal homology to the Saccharomyces cerevisiae TOP1 gene. Aguilera, A., Klein, H.L. Mol. Cell. Biol. (1990)
- Defects in SUMO (small ubiquitin-related modifier) conjugation and deconjugation alter cell sensitivity to DNA topoisomerase I-induced DNA damage. Jacquiau, H.R., van Waardenburg, R.C., Reid, R.J., Woo, M.H., Guo, H., Johnson, E.S., Bjornsti, M.A. J. Biol. Chem. (2005)
- Repair of topoisomerase I covalent complexes in the absence of the tyrosyl-DNA phosphodiesterase Tdp1. Liu, C., Pouliot, J.J., Nash, H.A. Proc. Natl. Acad. Sci. U.S.A. (2002)
- DNA topoisomerase I controls the kinetics of promoter activation and DNA topology in Saccharomyces cerevisiae. Di Mauro, E., Camilloni, G., Verdone, L., Caserta, M. Mol. Cell. Biol. (1993)
- Camptothecin resistance from a single mutation changing glycine 363 of human DNA topoisomerase I to cysteine. Benedetti, P., Fiorani, P., Capuani, L., Wang, J.C. Cancer Res. (1993)
- Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae. Mullen, J.R., Kaliraman, V., Ibrahim, S.S., Brill, S.J. Genetics (2001)
- Mutations in GCR3, a gene involved in the expression of glycolytic genes in Saccharomyces cerevisiae, suppress the temperature-sensitive growth of hpr1 mutants. Uemura, H., Pandit, S., Jigami, Y., Sternglanz, R. Genetics (1996)
- Yeast Tdp1 and Rad1-Rad10 function as redundant pathways for repairing Top1 replicative damage. Vance, J.R., Wilson, T.E. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Camptothecin sensitivity is mediated by the pleiotropic drug resistance network in yeast. Reid, R.J., Kauh, E.A., Bjornsti, M.A. J. Biol. Chem. (1997)
- Identification and characterization of the genes for two topoisomerase I-interacting proteins from Saccharomyces cerevisiae. Park, H., Sternglanz, R. Yeast (1999)
- The topoisomerase I gene from Candida albicans. Jiang, W., Gerhold, D., Kmiec, E.B., Hauser, M., Becker, J.M., Koltin, Y. Microbiology (Reading, Engl.) (1997)
- The genetic control of DS-RNA virus-like particles associated with Saccharomyces cerevisiae killer yeast. Mitchell, D.J., Herring, A.J., Bevan, E.A. Heredity (1976)
- A novel active DNA topoisomerase I in Leishmania donovani. Villa, H., Otero Marcos, A.R., Reguera, R.M., Balaña-Fouce, R., García-Estrada, C., Pérez-Pertejo, Y., Tekwani, B.L., Myler, P.J., Stuart, K.D., Bjornsti, M.A., Ordóñez, D. J. Biol. Chem. (2003)
- Functional dissection of the C-terminal domain of type II DNA topoisomerase from the kinetoplastid hemoflagellate Leishmania donovani. Sengupta, T., Mukherjee, M., Mandal, C., Das, A., Majumder, H.K. Nucleic Acids Res. (2003)