Gene Review:
Top1 - Topoisomerase 1
Drosophila melanogaster
Synonyms:
CG6146, DNA topoisomerase 1, DNA topoisomerase I, Dmel\CG6146, TOP1, ...
- Single-molecule study of DNA unlinking by eukaryotic and prokaryotic type-II topoisomerases. Charvin, G., Bensimon, D., Croquette, V. Proc. Natl. Acad. Sci. U.S.A. (2003)
- Knotting of the circular duplex DNA by type II DNA topoisomerase from Drosophila melanogaster. Hsieh, T. J. Biol. Chem. (1983)
- Loss of drug-stimulated topoisomerase II DNA breaks in living cells is different at two unrelated loci. Binaschi, M., Borgnetto, M.E., Capranico, G. Nucleic Acids Res. (2000)
- Topoisomerase I is essential in Cryptococcus neoformans: role In pathobiology and as an antifungal target. Del Poeta, M., Toffaletti, D.L., Rude, T.H., Dykstra, C.C., Heitman, J., Perfect, J.R. Genetics (1999)
- Topoisomerase I interacts with transcribed regions in Drosophila cells. Gilmour, D.S., Pflugfelder, G., Wang, J.C., Lis, J.T. Cell (1986)
- ATP-dependent DNA topoisonmerase from D. melanogaster reversibly catenates duplex DNA rings. Hsieh, T., Brutlag, D. Cell (1980)
- The ubiquitin ligase dTopors directs the nuclear organization of a chromatin insulator. Capelson, M., Corces, V.G. Mol. Cell (2005)
- Drosophila melanogaster topoisomerase IIIalpha preferentially relaxes a positively or negatively supercoiled bubble substrate and is essential during development. Plank, J.L., Chu, S.H., Pohlhaus, J.R., Wilson-Sali, T., Hsieh, T.S. J. Biol. Chem. (2005)
- Developmental regulation of DNA-topoisomerases during Drosophila embryogenesis. Gemkow, M.J., Dichter, J., Arndt-Jovin, D.J. Exp. Cell Res. (2001)
- Genotoxic profile of inhibitors of topoisomerases I (camptothecin) and II (etoposide) in a mitotic recombination and sex-chromosome loss somatic eye assay of Drosophila melanogaster. Sortibrán, A.N., Téllez, M.G., Rodríguez-Arnaiz, R. Mutat. Res. (2006)
- Protein kinase C phosphorylates topoisomerase II: topoisomerase activation and its possible role in phorbol ester-induced differentiation of HL-60 cells. Sahyoun, N., Wolf, M., Besterman, J., Hsieh, T., Sander, M., LeVine, H., Chang, K.J., Cuatrecasas, P. Proc. Natl. Acad. Sci. U.S.A. (1986)
- Gadd45, a p53-responsive stress protein, modifies DNA accessibility on damaged chromatin. Carrier, F., Georgel, P.T., Pourquier, P., Blake, M., Kontny, H.U., Antinore, M.J., Gariboldi, M., Myers, T.G., Weinstein, J.N., Pommier, Y., Fornace, A.J. Mol. Cell. Biol. (1999)
- Interaction in vitro of type III intermediate filament proteins with supercoiled plasmid DNA and modulation of eukaryotic DNA topoisomerase I and II activities. Li, G., Tolstonog, G.V., Sabasch, M., Traub, P. DNA Cell Biol. (2002)
- Cloning and characterization of the gene for the somatic form of DNA topoisomerase I from Xenopus laevis. Pandit, S.D., Richard, R.E., Sternglanz, R., Bogenhagen, D.F. Nucleic Acids Res. (1996)
- DNA superhelicity affects the formation of transcription preinitiation complex on eukaryotic genes differently. Mizutani, M., Ura, K., Hirose, S. Nucleic Acids Res. (1991)
- Cloning and characterization of Drosophila topoisomerase IIIbeta. Relaxation of hypernegatively supercoiled DNA. Wilson, T.M., Chen, A.D., Hsieh, T. J. Biol. Chem. (2000)
- Structure of the Drosophila DNA topoisomerase I gene and expression of messages with different lengths in the 3' untranslated region. Brown, S.D., Zhang, C.X., Chen, A.D., Hsieh, T.S. Gene (1998)
- A protein kinase activity tightly associated with Drosophila type II DNA topoisomerase. Sander, M., Nolan, J.M., Hsieh, T. Proc. Natl. Acad. Sci. U.S.A. (1984)
- Localization of specific topoisomerase I interactions within the transcribed region of active heat shock genes by using the inhibitor camptothecin. Gilmour, D.S., Elgin, S.C. Mol. Cell. Biol. (1987)
- Preferential cleavage of plasmid-based R-loops and D-loops by Drosophila topoisomerase IIIbeta. Wilson-Sali, T., Hsieh, T.S. Proc. Natl. Acad. Sci. U.S.A. (2002)
- DNA topoisomerase II from Drosophila melanogaster. Relaxation of supercoiled DNA. Osheroff, N., Shelton, E.R., Brutlag, D.L. J. Biol. Chem. (1983)
- Evidence that intergenic spacer repeats of Drosophila melanogaster rRNA genes function as X-Y pairing sites in male meiosis, and a general model for achiasmatic pairing. McKee, B.D., Habera, L., Vrana, J.A. Genetics (1992)
- Patterns of variation in the intergenic spacers of ribosomal DNA in Drosophila melanogaster support a model for genetic exchanges during X-Y pairing. Polanco, C., González, A.I., Dover, G.A. Genetics (2000)
- Novel HeLa topoisomerase II is the II beta isoform: complete coding sequence and homology with other type II topoisomerases. Austin, C.A., Sng, J.H., Patel, S., Fisher, L.M. Biochim. Biophys. Acta (1993)
- The gene encoding topoisomerase I from the human malaria parasite Plasmodium falciparum. Tosh, K., Kilbey, B. Gene (1995)
- Topoisomerase II-catalyzed ATP hydrolysis as monitored by thin-layer chromatography. Kingma, P.S., Fortune, J.M., Osheroff, N. Methods Mol. Biol. (2001)
- Association of topoisomerase I with transcriptionally active loci in Drosophila. Gilmour, D.S., Elgin, S.C. NCI monographs : a publication of the National Cancer Institute. (1987)