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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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MeSH term: ... of the gene. DEFA1 appeared to be at high copy number in all great apes studied; at one variable site..., against the Gag and Bet proteins were detected, by Western blotting, in all sample types from infected...Disease relevance of Pan troglodytes Adaptive evolution of the tumour suppressor BRCA1 in humans... / Synonyms: Pan troglodyte; troglodyte, Pan; troglodytes, Pan
Drosophila melanogaster
Gene: ... Disease relevance of pan Humans possess two Pygo proteins, both of which are required for TCF... HIV- 1 transcription on chromatin- assembled DNA in vitro. High impact information on pan Its... signaling. Biological context of pan LEF- 1 is an additional transcription factor that mediates... / Synonyms: Dm Pan; PAN; Pan
PAN1  -  Pan1p
Saccharomyces cerevisiae S288c
Gene: ... High impact information on PAN1 We suggest that Pan1p forms the core of an endocytic complex... providing the forces necessary for endocytosis. Here we show that the yeast endocytic protein Pan1p binds... to phosphorylate regions of Pan1p containing the LxxQxTG repeats, including the region responsible for binding... / Synonyms: Actin cytoskeleton-regulatory complex protein PAN1
Mus musculus
Gene: ... Disease relevance of Pan1 In both of these studies we observed the disappearance from the pancreas... additional minor response. Psychiatry related information on Pan1 Huntington' s disease of the endocrine... on Pan1 OT receptors have also been identified in other tissues, including the kidney, heart, thymus... / Synonyms: Pan-1; Pan1
MeSH term: ... polymorphisms, all involving CpG dinucleotides, and two shared human/ gorilla polymorphisms, one involving a Cp... chimpanzees form the conserved" framework" common to all KIR haplotypes in these species and upon which...Disease relevance of Pan paniscus A HERV- K provirus in chimpanzees, bonobos and gorillas... / Synonyms: paniscus, Pan
Homo sapiens
Gene: ... High impact information on PAN3 MMC showed positive antitumor activity on PAN- 3- JCK and PAN- 12- JCK, and 5- FU was effective on PAN- 12- JCK.... / Synonyms: PAB-dependent poly(A)-specific ribonuclease subunit PAN3; PAN deadenylation complex subunit 3; hPan3
PAN3  -  Pan3p
Saccharomyces cerevisiae S288c
Gene: ... High impact information on PAN3 We also provide evidence that the Pan2p/ Pan3p nuclease complex encodes the predominant alternative deadenylase. The importance of these amino acids for Pab1p- Pan3p... forkhead- associated domain interacts with the Pan3 subunit of the poly( A )- nuclease complex and that dun... / Synonyms: PAB-dependent poly(A)-specific ribonuclease subunit PAN3; PAN deadenylation complex subunit 3
PAN2  -  Pan2p
Saccharomyces cerevisiae S288c
Gene: ... Disease relevance of PAN2 We examined the effects of deletions of genes encoding deadenylase components Ccr4p and Pan2p and putative RNA- binding proteins Pub1p and Puf4p on the genome- wide pattern... information on PAN2 The strong conservation of Ccr4p, Caf1p, Pan2p, and Pan3p indicates... / Synonyms: PAB-dependent poly(A)-specific ribonuclease subunit PAN2; PAN deadenylation complex catalytic subunit 2
Homo sapiens
Gene: ... Disease relevance of USP52 Here, we present a 17- year- old male patient with FMF who subsequently developed PAN 2 weeks after hepatitis A infection. High impact information on USP52 As an extension of our cDNA analysis for deducing the coding sequences of unidentified human genes, we have newly determined... / Synonyms: PAB-dependent poly(A)-specific ribonuclease subunit PAN2; PAN deadenylation complex catalytic subunit 2; hPAN2
Escherichia coli str. K-12 substr. MG1655
Gene: ... Disease relevance of panB Cloning and sequencing of the Escherichia coli panB gene, which encodes ketopantoate hydroxymethyltransferase, and overexpression of the enzyme. High impact information on panB Escherichia coli ts9 strain manifests temperature- sensitive phenotype on LB media due to its mutation... / Synonyms: panA


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