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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Your search matched a total of 587 documents. Results 1 - 10.

Drosophila melanogaster
Gene: ... containing the 25 kb trx transcription unit identifies all sequences necessary for normal trx function...Disease relevance of trx Cysteine- rich portions expressed from trx cDNAs in Escherichia coli are capable of zinc binding in vitro, suggesting a possible function for the trx product as a metal- dependent... / Synonyms: TRX; Trx; Trx-G
Saccharomyces cerevisiae S288c
Gene: ... Disease relevance of TRX2 The disruption of both of the two Saccharomyces cerevisiae thioredoxin... impact information on TRX2 This is the first study that implicates thioredoxin activity in the regulation... with a thioredoxin subunit. Using a specific genetic screen, the TRX2 gene, one of two genes of S. cerevisiae... / Synonyms: TRX1
Homo sapiens
Gene: ... of subcellular localization of TRX and the chimeric protein harboring herpes simplex viral protein 16... Trx levels. Also the mammalian Trx system was inhibited by GS- Pt with similar efficiency( IC( 50)= 325 microM ), whereas neither the E. coli Trx system nor glutathione reductase were inhibited... / Synonyms: TRX; TRX1; Trx
Saccharomyces cerevisiae S288c
Gene: ... High impact information on TRX1 Our data further suggest that Skn7 and Yap1 co- operate on the TRX2 promoter, to induce transcription in response to oxidative stress. TRX2 is already known to be induced... expressed eight plant thioredoxins( six cytoplasmic and two chloroplastic) in yeast trx1, trx2 double mutant... / Synonyms: TRX2
trxA  -  TRX
Haemophilus influenzae 86-028NP
Gene: ... High impact information on trxA Cellular redox control is often mediated by oxidation and reduction of cysteine residues in the redox- sensitive proteins, where thioredoxin and glutaredoxin( Grx) play as electron donors for the oxidized proteins....
TRX3  -  Trx3p
Saccharomyces cerevisiae S288c
Gene: ... Disease relevance of TRX3 We cloned and expressed both proteins in Escherichia coli, and the recombinant Trx3 and Trr2 proteins were active in the insulin reduction assay. High impact information on TRX3 The TRX3 gene codes for a 14- kDa protein containing the characteristic thioredoxin active site( WCGPC...
Mus musculus
Gene: ... phosphorylation and the formation of intranuclear cofilin inclusions in mutant germ cells. Trx transgenic( Tg... overexpressing thioredoxin- 1. The present study suggests that overexpression of TRX- 1 suppresses H. felis... of TRX- 1 also attenuated pancreatic fibrosis and suppressed the activation of pancreatic stellate cells... / Synonyms: Trx; Trx1
Drosophila melanogaster
Gene: ... Psychiatry related information on Trx- 2 Among these we emphasize the identification of proteins..., and serine proteases ), as well as in signal transduction pathways. High impact information on Trx- 2... that can efficiently use Trx- 2 but not Trx- 1 as a reducing substrate. In its disulfide form, the 13- k... / Synonyms: DmTrx-2; DmelTrx-2; Trx
Chlamydophila caviae GPIC
Gene: ... High impact information on trx Analysis of the regions flanking mip identified three tightly linked open reading frames coding for predicted products with sequence similarity to asparagine tRNA ligase( AspS ), rRNA methylase( SpoU ), and thioredoxin( TrxA)....
Drosophila melanogaster
Gene: ... High impact information on TrxT Site- directed mutagenesis of C91 in DmGPx abrogated Trx peroxidase... and homology considerations based on 450 GPxs suggest peculiar features to determine Trx specificity:( i) a non... typical of tetrameric GPxs leading to flexibility of the C( R )- containing loop. TrxT and dhd... / Synonyms: DmTrxT; DmelTrxT


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