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Rhian M. Touyz

MRC Multidisciplinary Research Group on Hypertension

Clinical Research Institute of Montreal

University of Montreal

Quebec

Canada

[email]@ircm.qc.ca

Name/email consistency: high

 
 
 
 
 
 
 

Affiliations

  • MRC Multidisciplinary Research Group on Hypertension, Clinical Research Institute of Montreal, University of Montreal, Quebec, Canada. 1999 - 2005
  • Clinical Research Institute of Montreal, 110 Pine Avenue West, Montreal, Quebec H2W 1R7, Canada. 2000 - 2005
  • Canadian Institute of Health Research Multidisciplinary Research Group on Hypertension, Quebec, Canada. 2003
  • Clinical Research Institute of Montreal, Quebec, Canada. 2003
  • Laboratory of Experimental Hypertension, bLaboratory of Experimental Cardiovascular Biology, Clinical Research Institute of Montreal, University of Montreal, Canada. 2002
  • Department of Medicine, University of Witwatersrand, Johannesburg, South Africa. 1999

References

  1. p47phox associates with the cytoskeleton through cortactin in human vascular smooth muscle cells: role in NAD(P)H oxidase regulation by angiotensin II. Touyz, R.M., Yao, G., Quinn, M.T., Pagano, P.J., Schiffrin, E.L. Arterioscler. Thromb. Vasc. Biol. (2005) [Pubmed]
  2. Molecular and cellular mechanisms in vascular injury in hypertension: role of angiotensin II. Touyz, R.M. Curr. Opin. Nephrol. Hypertens. (2005) [Pubmed]
  3. Angiotensin II-dependent chronic hypertension and cardiac hypertrophy are unaffected by gp91phox-containing NADPH oxidase. Touyz, R.M., Mercure, C., He, Y., Javeshghani, D., Yao, G., Callera, G.E., Yogi, A., Lochard, N., Reudelhuber, T.L. Hypertension (2005) [Pubmed]
  4. Role of the actin cytoskeleton in angiotensin II signaling in human vascular smooth muscle cells. Touyz, R.M., Yao, G., Schiffrin, E.L. Can. J. Physiol. Pharmacol. (2005) [Pubmed]
  5. Magnesium in clinical medicine. Touyz, R.M. Front. Biosci. (2004) [Pubmed]
  6. Angiotensin II and endothelin-1 regulate MAP kinases through different redox-dependent mechanisms in human vascular smooth muscle cells. Touyz, R.M., Yao, G., Viel, E., Amiri, F., Schiffrin, E.L. J. Hypertens. (2004) [Pubmed]
  7. Reactive oxygen species, vascular oxidative stress, and redox signaling in hypertension: what is the clinical significance?. Touyz, R.M. Hypertension (2004) [Pubmed]
  8. Reactive oxygen species and angiotensin II signaling in vascular cells -- implications in cardiovascular disease. Touyz, R.M. Braz. J. Med. Biol. Res. (2004) [Pubmed]
  9. Reactive oxygen species in vascular biology: implications in hypertension. Touyz, R.M., Schiffrin, E.L. Histochem. Cell Biol. (2004) [Pubmed]
  10. Role of magnesium in the pathogenesis of hypertension. Touyz, R.M. Mol. Aspects Med. (2003) [Pubmed]
  11. Inhibitors of Na+/Mg2+ exchange activity attenuate the development of hypertension in angiotensin II-induced hypertensive rats. Touyz, R.M., Yao, G. J. Hypertens. (2003) [Pubmed]
  12. Recent advances in intracellular signalling in hypertension. Touyz, R.M. Curr. Opin. Nephrol. Hypertens. (2003) [Pubmed]
  13. The role of angiotensin II in regulating vascular structural and functional changes in hypertension. Touyz, R.M. Curr. Hypertens. Rep. (2003) [Pubmed]
  14. c-Src induces phosphorylation and translocation of p47phox: role in superoxide generation by angiotensin II in human vascular smooth muscle cells. Touyz, R.M., Yao, G., Schiffrin, E.L. Arterioscler. Thromb. Vasc. Biol. (2003) [Pubmed]
  15. Redox-dependent MAP kinase signaling by Ang II in vascular smooth muscle cells: role of receptor tyrosine kinase transactivation. Touyz, R.M., Cruzado, M., Tabet, F., Yao, G., Salomon, S., Schiffrin, E.L. Can. J. Physiol. Pharmacol. (2003) [Pubmed]
  16. Up-regulation of vascular and renal mitogen-activated protein kinases in hypertensive rats is normalized by inhibitors of the Na+/Mg2+ exchanger. Touyz, R.M., Yao, G. Clin. Sci. (2003) [Pubmed]
  17. Role of endothelin in human hypertension. Touyz, R.M., Schiffrin, E.L. Can. J. Physiol. Pharmacol. (2003) [Pubmed]
  18. Modulation of vascular smooth muscle cell growth by magnesium-role of mitogen-activated protein kinases. Touyz, R.M., Yao, G. J. Cell. Physiol. (2003) [Pubmed]
  19. Redox-dependent signalling by angiotensin II and vascular remodelling in hypertension. Touyz, R.M., Tabet, F., Schiffrin, E.L. Clin. Exp. Pharmacol. Physiol. (2003) [Pubmed]
  20. Reactive oxygen species in vascular biology: role in arterial hypertension. Touyz, R.M. Expert. Rev. Cardiovasc. Ther (2003) [Pubmed]
  21. Increased angiotensin II-mediated Src signaling via epidermal growth factor receptor transactivation is associated with decreased C-terminal Src kinase activity in vascular smooth muscle cells from spontaneously hypertensive rats. Touyz, R.M., Wu, X.H., He, G., Salomon, S., Schiffrin, E.L. Hypertension (2002) [Pubmed]
  22. Inhibition of mitogen-activated protein/extracellular signal-regulated kinase improves endothelial function and attenuates Ang II-induced contractility of mesenteric resistance arteries from spontaneously hypertensive rats. Touyz, R.M., Deschepper, C., Park, J.B., He, G., Chen, X., Neves, M.F., Virdis, A., Schiffrin, E.L. J. Hypertens. (2002) [Pubmed]
  23. Expression of a functionally active gp91phox-containing neutrophil-type NAD(P)H oxidase in smooth muscle cells from human resistance arteries: regulation by angiotensin II. Touyz, R.M., Chen, X., Tabet, F., Yao, G., He, G., Quinn, M.T., Pagano, P.J., Schiffrin, E.L. Circ. Res. (2002) [Pubmed]
  24. Recent advances in angiotensin II signaling. Touyz, R.M., Berry, C. Braz. J. Med. Biol. Res. (2002) [Pubmed]
  25. Effects of low dietary magnesium intake on development of hypertension in stroke-prone spontaneously hypertensive rats: role of reactive oxygen species. Touyz, R.M., Pu, Q., He, G., Chen, X., Yao, G., Neves, M.F., Viel, E. J. Hypertens. (2002) [Pubmed]
  26. p38 Map kinase regulates vascular smooth muscle cell collagen synthesis by angiotensin II in SHR but not in WKY. Touyz, R.M., He, G., El Mabrouk, M., Schiffrin, E.L. Hypertension (2001) [Pubmed]
  27. Angiotensin II type I receptor modulates intracellular free Mg2+ in renally derived cells via Na+-dependent Ca2+-independent mechanisms. Touyz, R.M., Mercure, C., Reudelhuber, T.L. J. Biol. Chem. (2001) [Pubmed]
  28. Role of c-Src in the regulation of vascular contraction and Ca2+ signaling by angiotensin II in human vascular smooth muscle cells. Touyz, R.M., Wu, X.H., He, G., Park, J.B., Chen, X., Vacher, J., Rajapurohitam, V., Schiffrin, E.L. J. Hypertens. (2001) [Pubmed]
  29. Increased generation of superoxide by angiotensin II in smooth muscle cells from resistance arteries of hypertensive patients: role of phospholipase D-dependent NAD(P)H oxidase-sensitive pathways. Touyz, R.M., Schiffrin, E.L. J. Hypertens. (2001) [Pubmed]
  30. Src is an important mediator of extracellular signal-regulated kinase 1/2-dependent growth signaling by angiotensin II in smooth muscle cells from resistance arteries of hypertensive patients. Touyz, R.M., He, G., Wu, X.H., Park, J.B., Mabrouk, M.E., Schiffrin, E.L. Hypertension (2001) [Pubmed]
  31. Oxidative stress and vascular damage in hypertension. Touyz, R.M. Curr. Hypertens. Rep. (2000) [Pubmed]
  32. Molecular and cellular mechanisms regulating vascular function and structure--implications in the pathogenesis of hypertension. Touyz, R.M. Can. J. Cardiol (2000) [Pubmed]
  33. Endothelin-A-receptor blockade improves renal function and doubles the lifespan of stroke-prone spontaneously hypertensive rats. Touyz, R.M., Turgeon, A., Schiffrin, E.L. J. Cardiovasc. Pharmacol. (2000) [Pubmed]
  34. Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells. Touyz, R.M., Schiffrin, E.L. Pharmacol. Rev. (2000) [Pubmed]
  35. Angiotensin II stimulates DNA and protein synthesis in vascular smooth muscle cells from human arteries: role of extracellular signal-regulated kinases. Touyz, R.M., Deng, L.Y., He, G., Wu, X.H., Schiffrin, E.L. J. Hypertens. (1999) [Pubmed]
  36. Magnesium supplementation attenuates, but does not prevent, development of hypertension in spontaneously hypertensive rats. Touyz, R.M., Milne, F.J. Am. J. Hypertens. (1999) [Pubmed]
  37. Activation of the Na(+)-H+ exchanger modulates angiotensin II-stimulated Na(+)-dependent Mg2+ transport in vascular smooth muscle cells in genetic hypertension. Touyz, R.M., Schiffrin, E.L. Hypertension (1999) [Pubmed]
 
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