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Chemical Compound Review

KST-1B9359     [1-(5,8-dihydroxy-1,4-dioxo- naphthalen-2...

Synonyms: NSC-110263, NSC-373954, AC1L2OAD, NSC110263, NSC373954, ...
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High impact information on beta-Hydroxyisovalerylshikonin


  1. Involvement of tumor necrosis factor receptor-associated protein 1 (TRAP1) in apoptosis induced by beta-hydroxyisovalerylshikonin. Masuda, Y., Shima, G., Aiuchi, T., Horie, M., Hori, K., Nakajo, S., Kajimoto, S., Shibayama-Imazu, T., Nakaya, K. J. Biol. Chem. (2004) [Pubmed]
  2. Beta-hydroxyisovalerylshikonin induces apoptosis in human leukemia cells by inhibiting the activity of a polo-like kinase 1 (PLK1). Masuda, Y., Nishida, A., Hori, K., Hirabayashi, T., Kajimoto, S., Nakajo, S., Kondo, T., Asaka, M., Nakaya, K. Oncogene (2003) [Pubmed]
  3. beta-Hydroxyisovalerylshikonin induces apoptosis and G0/G1 cell-cycle arrest of endometriotic stromal cells: a preliminary in vitro study. Nishida, M., Nasu, K., Ueda, T., Yuge, A., Takai, N., Narahara, H. Hum. Reprod. (2006) [Pubmed]
  4. beta-hydroxyisovalerylshikonin inhibits the cell growth of various cancer cell lines and induces apoptosis in leukemia HL-60 cells through a mechanism different from those of Fas and etoposide. Hashimoto, S., Xu, M., Masuda, Y., Aiuchi, T., Nakajo, S., Cao, J., Miyakoshi, M., Ida, Y., Nakaya, K. J. Biochem. (1999) [Pubmed]
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