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Chemical Compound Review:

PubChem7762 2-nitrobenzaldehyde

Synonyms: CHEMBL166559, CPD-9059, NSC-5713, ACMC-1AOC2, CCRIS 2322, ...

Nakano, M. et al., Abbruzzetti, S. et al., Mulder, P.P. et al., Cooper, K.M. et al., Steinbrecher, K. et al., et al.

Mulder, Zuidema, Keestra, Kooij, Elbers, van Rhijn,

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High impact information on NSC 5713

PL and 2-nitrobenzaldehyde were excellent substrates, and no measurable activity was observed with short chain aliphatic aldehydes; substrate specificity of PL reductase was obviously different from those of yeast aldo-keto reductases (AKRs) so far purified [1].
We have developed an instrumental setup that uses transient absorption to monitor protein folding/unfolding processes following a laser-induced, ultrafast release of protons from o-nitrobenzaldehyde [2].
The method is based on the acid-catalysed hydrolysis of tissue-bound metabolites to free DSH and in situ derivatisation with 2-nitrobenzaldehyde to the corresponding nitrophenyl derivative NPDSH [3].
Prawn samples were derivatized with o-nitrobenzaldehyde, extracted into ethyl acetate, washed with hexane and applied to a competitive enzyme immunoassay based on a rabbit polyclonal antiserum [4].

Associations of NSC 5713 with other chemical compounds

Improved gas chromatographic method for determination of daminozide by alkaline hydrolysis and 2-nitrobenzaldehyde derivatization and survey results of daminozide in agricultural products [5].

Analytical, diagnostic and therapeutic context of NSC 5713

To answer this question, a method based upon the previously reported liquid chromatography/tandem mass spectrometry determination of the semicarbazone of o-nitrobenzaldehyde was utilized [6].

References

Purification, molecular cloning, and catalytic activity of Schizosaccharomyces pombe pyridoxal reductase. A possible additional family in the aldo-keto reductase superfamily. Nakano, M., Morita, T., Yamamoto, T., Sano, H., Ashiuchi, M., Masui, R., Kuramitsu, S., Yagi, T. J. Biol. Chem. (1999) [Pubmed]
Kinetics of histidine deligation from the heme in GuHCl-unfolded Fe(III) cytochrome C studied by a laser-induced pH-jump technique. Abbruzzetti, S., Viappiani, C., Small, J.R., Libertini, L.J., Small, E.W. J. Am. Chem. Soc. (2001) [Pubmed]
Determination of nifursol metabolites in poultry muscle and liver tissue. Development and validation of a confirmatory method. Mulder, P.P., Zuidema, T., Keestra, N.G., Kooij, P.J., Elbers, I.J., van Rhijn, J.A. The Analyst. (2005) [Pubmed]
Detection of 3-amino-2-oxazolidinone (AOZ), a tissue-bound metabolite of the nitrofuran furazolidone, in prawn tissue by enzyme immunoassay. Cooper, K.M., Elliott, C.T., Kennedy, D.G. Food additives and contaminants. (2004) [Pubmed]
Improved gas chromatographic method for determination of daminozide by alkaline hydrolysis and 2-nitrobenzaldehyde derivatization and survey results of daminozide in agricultural products. Steinbrecher, K., Saxton, W.L., Oehler, G.A. Journal - Association of Official Analytical Chemists. (1990) [Pubmed]
The determination of semicarbazide (N-aminourea) in commercial bread products by liquid chromatography-mass spectrometry. Noonan, G.O., Warner, C.R., Hsu, W., Begley, T.H., Perfetti, G.A., Diachenko, G.W. J. Agric. Food Chem. (2005) [Pubmed]

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