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Chemical Compound Review

Aminozide     3-(dimethylaminocarbamoyl) propanoic acid

Synonyms: Daminozide, DMASA, Dimas, Kylar, diaminozide, ...
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Disease relevance of B-Nine

  • Five patients had signs and symptoms of encephalopathy before shunting; in four, the disease was classified as Child's class C and in one, as Child's class B. Nine-millimeter self-expandable metallic stents were used in all patients [1].
  • Myocardial infarction reached the right bundle branch more than 8 mm above the moderator band in all of group A, whereas myocardial infarction reached the right bundle branch less than 3 mm above the moderator band in only three patients in group B. Nine hearts in group A showed significant necrosis of the right bundle branch [2].
  • Rats were given diethylnitrosamine (DEN) at 200 mg/kg body weight intraperitoneally and then 2 weeks later were given daminozide at 20,000 ppm or daminozide plus UDMH at 75, 150, or 300 ppm in the diet for 6 weeks and were then killed; all rats underwent a partial (two-thirds) hepatectomy (PH) at week 3 [3].

High impact information on B-Nine


Analytical, diagnostic and therapeutic context of B-Nine


  1. Transjugular intrahepatic portosystemic shunt: early experience with a flexible trocar/catheter system. Maynar, M., Cabrera, J., Pulido-Duque, J.M., Reyes, R., Górriz, E., Rostagno, R., Ferral, H., Castañeda-Zúñiga, W.R. AJR. American journal of roentgenology. (1993) [Pubmed]
  2. A quantitative histopathological study of right bundle branch block complicating acute anteroseptal myocardial infarction. Okabe, M., Fukuda, K., Nakashima, Y., Hiroki, T., Arakawa, K., Kikuchi, M. British heart journal. (1991) [Pubmed]
  3. Lack of carcinogenicity of daminozide, alone or in combination with its contaminant 1,1-dimethylhydrazine, in a medium-term bioassay. Cabral, R., Hakoi, K., Hoshiya, T., Hasegawa, R., Ito, N. Teratog., Carcinog. Mutagen. (1995) [Pubmed]
  4. Transformation of the plant growth regulator daminozide (Alar) and structurally related compounds with CuII ions: oxidation versus hydrolysis. Huang, C.H., Stone, A.T. Environ. Sci. Technol. (2003) [Pubmed]
  5. Pesticides and food safety. Fan, A.M., Jackson, R.J. Regulatory toxicology and pharmacology : RTP. (1989) [Pubmed]
  6. Improved gas chromatographic method for determination of daminozide by alkaline hydrolysis and 2-nitrobenzaldehyde derivatization and survey results of daminozide in agricultural products. Steinbrecher, K., Saxton, W.L., Oehler, G.A. Journal - Association of Official Analytical Chemists. (1990) [Pubmed]
  7. DNA methylation in rat liver by daminozide, 1,1-dimethylhydrazine, and dimethylnitrosamine. Sagelsdorff, P., Lutz, W.K., Schlatter, C. Fundamental and applied toxicology : official journal of the Society of Toxicology. (1988) [Pubmed]
  8. Determination of daminozide in apples by gas chromatography/chemical ionization mass spectrometry. Liu, C.H., Mattern, G.C., Singer, G.M., Rosen, J.D. Journal - Association of Official Analytical Chemists. (1989) [Pubmed]
  9. Penetrating chest injuries in civilian practice. Adegboye, V.O., Ladipo, J.K., Brimmo, I.A., Adebo, A.O. African journal of medicine and medical sciences. (2001) [Pubmed]
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