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Chemical Compound Review

Acetidin     ethyl ethanoate

Synonyms: Essigester, AcOEt, Ethylazetat, Aethylacetat, Acetoxyethane, ...
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Disease relevance of acetic acid ethyl ester


Psychiatry related information on acetic acid ethyl ester


High impact information on acetic acid ethyl ester


Chemical compound and disease context of acetic acid ethyl ester


Biological context of acetic acid ethyl ester


Anatomical context of acetic acid ethyl ester

  • This was followed by a wave of mitochondrial depolarization (measured using tetramethylrhodamine ethyl ester [TMRE]), consistent with Ca2+ uptake into mitochondria as the Ca2+ wave traveled across the cell [24].
  • A number of proteins, as well as RNA and DNA, dissolved in these alcohols readily crossed the lipidized membranes, whereas the same biopolymers placed in nondissolving solvents (e.g., hexane and ethyl acetate) or in those unable to dissolve lipids (e.g., water and dimethyl sulfoxide) exhibited little transmembrane transport [25].
  • Macrophages released the majority of the ethyl acetate-soluble metabolites that they produced into the surrounding medium [26].
  • Metabolism of benzo(a)pyrene and its major metabolites to ethyl acetate-soluble and water-soluble metabolites by cultured rodent trachea [27].
  • When deuterium was present in the ethyl (ester) groups, increases in the rate of 2-methyl hydroxylation were observed in rat liver microsomes and with purified P-450 beta NF-B (but not with P-450PB-B) [28].

Associations of acetic acid ethyl ester with other chemical compounds


Gene context of acetic acid ethyl ester

  • Overexpression of Eht1 and Eeb1 did not enhance medium-chain fatty acid ethyl ester content, which is probably due to the bifunctional synthesis and hydrolysis activity [34].
  • The Saccharomyces cerevisiae EHT1 and EEB1 genes encode novel enzymes with medium-chain fatty acid ethyl ester synthesis and hydrolysis capacity [34].
  • High throughput screening identified 2-acetamido-thiazolylthio acetic ester 1 as an inhibitor of cyclin-dependent kinase 2 (CDK2) [35].
  • Pharmacologically, the effects of DHPG were partially/completely reduced by the mGluR1 antagonists, 7-hydrox-iminocyclopropan[b]chromen-1a-carboxylic acid ethyl ester and (+)-2-methyl-4-carboxyphenylglycine [36].
  • However, pretreatment with the competitive NMDA receptor antagonist CGP39551 [(E)-(+/-)-2-amino-4-methyl-5-phosphono-3-pentenoic acid ethyl ester] (10 mg/kg i.p.) did not potentiate the LMA effect of 0.1 mg/kg nicotine as seen with Ro 25-6981 [37].

Analytical, diagnostic and therapeutic context of acetic acid ethyl ester

  • Lipids in the glomeruli and media were extracted with ethyl acetate, and were purified and fractionated by HPLC [38].
  • Using high-pressure liquid chromatography, the ethyl acetate-soluble metabolites were separated into three major groups, phenols, quinones, and dihydrodiols, including peaks of three unknown materials [39].
  • After 0, 15, 30, 60, 90, and 120 min of incubation, 0.1-ml samples were extracted into ethyl acetate and analyzed by gas-liquid chromatography (1.8-m X 2-mm column packed with 3% OV225 on 100/120 Supelcoport; oven at 180 degrees; injection port and nitrogen-phosphorus detector at 230 degrees) [40].
  • Molecular cloning, sequencing, and expression of human myocardial fatty acid ethyl ester synthase-III cDNA [41].
  • Gamma-glutamylcysteine ethyl ester effectively reduced infarct size in a dose-dependent manner (mean +/- SEM 26.4 +/- 3.5% in the low dose group [3 mg/kg, n = 10] and 19.0 +/- 3.4% in the high dose group [10 mg/kg, n = 10]; each p < 0.05 vs. the value in the control group [40.6 +/- 4.8%, n = 10]) [18].


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