Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

AC1L3FTZ (2S)-2-[[(3R,4S)-5-chloro- 4,8-dihydroxy-3...

Synonyms: AC1Q5QQF, AR-1K4361, 4-Hydroxyochratoxin A, (4R)-4-Hydroxyochratoxin A

Jonsyn-Ellis, F.E., Størmer, F.C. et al., Størmer, F.C. et al.

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High impact information on 4-Hydroxyochratoxin A

The results indicate that the microsomal hydroxylation system is a cytochrome P-450 and that different species are involved in the formation of the two epimeric forms of 4-hydroxyochratoxin A [1].
Formation of 4-hydroxyochratoxin A from ochratoxin A by rat liver microsomes [2].
There were significant differences in the frequency of exposure to some mycotoxins: ochratoxin A (OTA), p < 0.01; 4-hydroxyochratoxin A (4R-OTA), p < 0.002; aflatoxin M1 (AFM 1), p < 0.04; aflatoxicol (AFL), p < 0.03; aflatoxin B2 (AFB2), p < 0.04 [3].

References

Formation of (4R)- and (4S)-4-hydroxyochratoxin A from ochratoxin A by liver microsomes from various species. Størmer, F.C., Hansen, C.E., Pedersen, J.I., Hvistendahl, G., Aasen, A.J. Appl. Environ. Microbiol. (1981) [Pubmed]
Formation of 4-hydroxyochratoxin A from ochratoxin A by rat liver microsomes. Størmer, F.C., Pedersen, J.I. Appl. Environ. Microbiol. (1980) [Pubmed]
Seasonal variation in exposure frequency and concentration levels of aflatoxins and ochratoxins in urine samples of boys and girls. Jonsyn-Ellis, F.E. Mycopathologia (2001) [Pubmed]

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