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Chemical Compound Review

TRIDECANONE     tridecan-2-one

Synonyms: Tridecan-2-one, CHEMBL480097, CPD-7901, ACMC-1AQBG, AG-G-03818, ...
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Disease relevance of TRIDECANONE

  • Pseudomonas cepacia 4G9 utilizes 2-tridecanone as its sole carbon source and has been shown to be resistant to a variety of antibiotics [1].
  • The bacteria (tentatively identified as Ralstonia sp.) exhibited strong monooxygenase activity growing on 2-tridecanone as sole source of carbon [2].

High impact information on TRIDECANONE

  • Heating both stimuli sources to 37 degrees C (body temperature) from 23 degrees C (room temperature) increased vapor concentration by 5.0 and 6.9 times, respectively, for heptyl benzene and 2-tridecanone [3].
  • Fatty acid elongation in the biosynthesis of (Z)-10-heptadecen-2-one and 2-tridecanone in ejaculatory bulb microsomes of Drosophila buzzatii [4].
  • Leaf extracts of L. hirsutum f. glabratum accessions that contain significant quantities of 2-tridecanone and/or trans-caryophyllene could be useful for managing populations of spider mites, which could reduce reliance on synthetic pesticides [5].


  1. Resistance plasmids in Pseudomonas cepacia 4G9. Williams, J.A., Yeggy, J.P., Field, C.C., Markovetz, A.J. J. Bacteriol. (1979) [Pubmed]
  2. A fatty acid alpha-ketol, a product of the plant lipoxygenase pathway, is oxidized to 3(Z)-dodecendioic acid by a bacterial monooxygenase. Schneider, C., Wein, M., Harmsen, D., Schreier, P. Biochem. Biophys. Res. Commun. (1997) [Pubmed]
  3. Chemical boundaries for detection of eye irritation in humans from homologous vapors. Cometto-Muñiz, J.E., Cain, W.S., Abraham, M.H., Sánchez-Moreno, R. Toxicol. Sci. (2006) [Pubmed]
  4. Fatty acid elongation in the biosynthesis of (Z)-10-heptadecen-2-one and 2-tridecanone in ejaculatory bulb microsomes of Drosophila buzzatii. Skiba, P.J., Jackson, L.L. Insect Biochem. Mol. Biol. (1994) [Pubmed]
  5. Natural products: repellency and toxicity of wild tomato leaf extracts to the two-spotted spider mite, Tetranychus urticae Koch. Antonious, G.F., Snyder, J.C. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. (2006) [Pubmed]
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