Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

AGN-PC-0084VU methyl 2-amino-2-phenyl-ethanoate

Synonyms: SureCN283419, Enamine_005656, AG-C-13161, CBDivE_003088, BBL008668, ...

Sasaki, K. et al., Wallace, D.J. et al.

Wallace, Goodman, Kennedy, Davies, Cowden, Ashwood, Cottrell, Dolling, Reider,

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High impact information on Methyl phenylglycine

The NK-1 receptor antagonist 1 has been prepared in seven steps from phenylglycine methyl ester [1].
The absolute configuration of pectenotoxin-6 (4, PTX6), found in association with diarrhetic shellfish poisoning, was identified by NMR spectroscopy using a chiral anisotropic reagent, phenylglycine methyl ester (PGME), which was condensed with a carboxyl group of 4 [2].

References

A double ring closing metathesis reaction in the rapid, enantioselective synthesis of NK-1 receptor antagonists. Wallace, D.J., Goodman, J.M., Kennedy, D.J., Davies, A.J., Cowden, C.J., Ashwood, M.S., Cottrell, I.F., Dolling, U.H., Reider, P.J. Org. Lett. (2001) [Pubmed]
Identification of the absolute configuration of pectenotoxin-6, a polyether macrolide compound, by NMR spectroscopic method using a chiral anisotropic reagent, phenylglycine methyl ester. Sasaki, K., Satake, M., Yasumoto, T. Biosci. Biotechnol. Biochem. (1997) [Pubmed]

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