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Chemical Compound Review

anthrylamine     anthracen-1-amine

Synonyms: Anthracenamine, CCRIS 749, CHEMBL82321, A38606_ALDRICH, AG-G-22102, ...
 
 
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High impact information on AMINOANTHRACENE

  • With AAF and Aroclor-induced preparations, supplementation with cytosol produces a slight but significant increase in activation, but interpretation is complicated by the fact that Aroclor 105,000 x g supernatant fraction (S105) alone efficiently activates AAF, AF and AA [1].
  • On the other hand, PC-VI had no effect on the DNA repair systems for B[a]P- or AA-induced mutagenesis [2].
  • Furthermore, OBP functionality, as determined by measuring the binding of the fluorescent ligand 1-aminoanthracene, was partially lost only when incubating HNE levels and exposure time to HNE exceeded physiological values in nasal mucosa [3].
  • Halothane bound to the cavity in the beta-barrel of porcine odorant binding protein with dissociation constants of 0.46 +/- 0.10 mM and 0.43 +/- 0.12 mM determined using fluorescence quenching and competitive binding with 1-aminoanthracene, respectively [4].
 

Biological context of AMINOANTHRACENE

References

  1. Enhancement of S9 activation by S105 cytosolic fraction. Forster, R., Green, M.H., Priestley, A. Carcinogenesis (1981) [Pubmed]
  2. Interaction of pine cone extract fraction VI with mutagens. Lee, H., Aoki, K., Sakagami, H., Yoshida, T., Kuroiwa, Y. Mutat. Res. (1993) [Pubmed]
  3. Odorant binding protein has the biochemical properties of a scavenger for 4-hydroxy-2-nonenal in mammalian nasal mucosa. Grolli, S., Merli, E., Conti, V., Scaltriti, E., Ramoni, R. FEBS J. (2006) [Pubmed]
  4. Binding of the volatile general anesthetics halothane and isoflurane to a mammalian beta-barrel protein. Johansson, J.S., Manderson, G.A., Ramoni, R., Grolli, S., Eckenhoff, R.G. FEBS J. (2005) [Pubmed]
 
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