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Chemical Compound Review: 

SureCN11156265     1-[2-[(2,4-dichlorophenyl) methoxy]octyl]im...

Synonyms: AC1Q5RII, LS-78376, RS-37367, CTK8D6695, AR-1B9682, ...
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High impact information on 1-[2-[(2,4-dichlorophenyl)methoxy]octyl]imidazole

  • Periovulatory stumptailed macaque monkeys were administered intravaginally 1 ml of Ramses Contraceptive Vaginal Jelly (C. Schmid Products Company, Little Fall, NJ), or a pluronic gel formulation containing 0, 0.1, or 1.0% of a new spermicidal compound, RS-37367 [1].
  • Short-term (5-minute) exposure of spermatozoa to concentrations of RS-37367 not immediately spermatostatic resulted in progressive immobilization of spermatozoa [2].
 

Anatomical context of 1-[2-[(2,4-dichlorophenyl)methoxy]octyl]imidazole

  • The spermatostatic potencies of a new vaginal contraceptive agent, RS-37367, and a standard surfactant compound, nonoxynol-9, have been compared by using ejaculated dog and human spermatozoa [2].

References

  1. Evaluation of the in vivo efficacy of a new vaginal contraceptive agent in stumptailed macaques. Zaneveld, L.J., Burns, J.W., Goodpasture, J.C., Vickery, B.H. Fertil. Steril. (1984) [Pubmed]
  2. Assessment of a new spermicidal agent against ejaculated dog and human spermatozoa in vitro. Vickery, B.H., Goodpasture, J.C., Bergstrom, K., Walker, K.A., Overstreet, J.W., Katz, D.F. Fertil. Steril. (1983) [Pubmed]
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