Chemical Compound Review:
NONOXYNOL 2-(4-nonylphenoxy)ethanol
Synonyms:
Egyptol, Koromex, Nonoxinol, Nonoxinols, Nonoxynols, ...
Munetz,
Griffin,
Doncel,
Chandra,
Fichorova,
Fichorova,
Zhou,
Ratnam,
Atanassova,
Jiang,
Strick,
Neurath,
Fichorova,
Tucker,
Anderson,
Patton,
Cosgrove Sweeney,
Rabe,
Hillier,
Howett,
Neely,
Christensen,
Wigdahl,
Krebs,
Malamud,
Patrick,
Pickel,
Welsh,
Reed,
Ward,
Budgeon,
Kreider,
Jain,
Li,
Nucatola,
Minoo,
Felix,
Weber,
Nunn,
O'Connor,
Jeffries,
Kitchen,
McCormack,
Stott,
Almond,
Stone,
Darbyshire,
Van Damme,
Ramjee,
Alary,
Vuylsteke,
Chandeying,
Rees,
Sirivongrangson,
Mukenge-Tshibaka,
Ettiègne-Traoré,
Uaheowitchai,
Karim,
Mâsse,
Perriëns,
Laga,
Hoffman,
Taha,
Padian,
Kelly,
Welch,
Martinson,
Kumwenda,
Rosenberg,
Chilongozi,
Brown,
Chirenje,
Richardson,
- A controlled trial of nonoxynol 9 film to reduce male-to-female transmission of sexually transmitted diseases. Roddy, R.E., Zekeng, L., Ryan, K.A., Tamoufé, U., Weir, S.S., Wong, E.L. N. Engl. J. Med. (1998)
- Nonoxynol 9 cream for genital herpes simplex. Donsky, H.J. N. Engl. J. Med. (1979)
- Passive cannabis smoke exposure and oral fluid testing. II. Two studies of extreme cannabis smoke exposure in a motor vehicle. Niedbala, R.S., Kardos, K.W., Fritch, D.F., Kunsman, K.P., Blum, K.A., Newland, G.A., Waga, J., Kurtz, L., Bronsgeest, M., Cone, E.J. Journal of analytical toxicology. (2005)
- Use of the Sequential Intercept Model as an approach to decriminalization of people with serious mental illness. Munetz, M.R., Griffin, P.A. Psychiatric services (Washington, D.C.) (2006)
- Efficacy of nonoxynol 9 contraceptive sponge use in preventing heterosexual acquisition of HIV in Nairobi prostitutes. Kreiss, J., Ngugi, E., Holmes, K., Ndinya-Achola, J., Waiyaki, P., Roberts, P.L., Ruminjo, I., Sajabi, R., Kimata, J., Fleming, T.R. JAMA (1992)
- Birth defects and vaginal spermicides. Shapiro, S., Slone, D., Heinonen, O.P., Kaufman, D.W., Rosenberg, L., Mitchell, A.A., Helmrich, S.P. JAMA (1982)
- Effectiveness of COL-1492, a nonoxynol-9 vaginal gel, on HIV-1 transmission in female sex workers: a randomised controlled trial. Van Damme, L., Ramjee, G., Alary, M., Vuylsteke, B., Chandeying, V., Rees, H., Sirivongrangson, P., Mukenge-Tshibaka, L., Ettiègne-Traoré, V., Uaheowitchai, C., Karim, S.S., Mâsse, B., Perriëns, J., Laga, M. Lancet (2002)
- Inactivation of HTLV-III/LAV-infected cultures of normal human lymphocytes by nonoxynol-9 in vitro. Hicks, D.R., Martin, L.S., Getchell, J.P., Heath, J.L., Francis, D.P., McDougal, J.S., Curran, J.W., Voeller, B. Lancet (1985)
- A broad-spectrum microbicide with virucidal activity against sexually transmitted viruses. Howett, M.K., Neely, E.B., Christensen, N.D., Wigdahl, B., Krebs, F.C., Malamud, D., Patrick, S.D., Pickel, M.D., Welsh, P.A., Reed, C.A., Ward, M.G., Budgeon, L.R., Kreider, J.W. Antimicrob. Agents Chemother. (1999)
- Nonoxynol-9: differential antibacterial activity and enhancement of bacterial adherence to vaginal epithelial cells. Hooton, T.M., Fennell, C.L., Clark, A.M., Stamm, W.E. J. Infect. Dis. (1991)
- Biocompatibility of solid-dosage forms of anti-human immunodeficiency virus type 1 microbicides with the human cervicovaginal mucosa modeled ex vivo. Trifonova, R.T., Pasicznyk, J.M., Fichorova, R.N. Antimicrob. Agents Chemother. (2006)
- Inhibition of growth of Chlamydia trachomatis by nonoxynol-9 in vitro. Benes, S., McCormack, W.M. Antimicrob. Agents Chemother. (1985)
- The effect of nonoxynol-9 and chlorhexidine on HIV and sperm in vitro. Harrison, C., Chantler, E. International journal of STD & AIDS. (1998)
- The molecular basis of nonoxynol-9-induced vaginal inflammation and its possible relevance to human immunodeficiency virus type 1 transmission. Fichorova, R.N., Tucker, L.D., Anderson, D.J. J. Infect. Dis. (2001)
- Nonoxynol-9 induces apoptosis of endometrial explants by both caspase-dependent and -independent apoptotic pathways. Jain, J.K., Li, A., Nucatola, D.L., Minoo, P., Felix, J.C. Biol. Reprod. (2005)
- Nonoxynol-9 in lubricated condoms. Results of a study in female prostitutes. Ward, H., De La Court, A., Kitchen, V. Sexually transmitted diseases. (1996)
- The inhibitory effect of spermicidal agents on replication of HSV-2 and HIV-1 in-vitro. Jennings, R., Clegg, A. J. Antimicrob. Chemother. (1993)
- Primate model for the evaluation of vaginal contraceptives. Zaneveld, L.J., Bhattacharyya, A.K., Kim, D.S., Schumacher, G.F., Beluhan, Z. Am. J. Obstet. Gynecol. (1977)
- Nonoxynol-9 100 mg gel: multi-site safety study from sub-Saharan Africa. Hoffman, I.F., Taha, T.E., Padian, N.S., Kelly, C.W., Welch, J.D., Martinson, F.E., Kumwenda, N.I., Rosenberg, Z.F., Chilongozi, D.A., Brown, J.M., Chirenje, M., Richardson, B.A. AIDS (2004)
- The cat/feline immunodeficiency virus model for transmucosal transmission of AIDS: nonoxynol-9 contraceptive jelly blocks transmission by an infected cell inoculum. Moench, T.R., Whaley, K.J., Mandrell, T.D., Bishop, B.D., Witt, C.J., Cone, R.A. AIDS (1993)
- The effects of three nonoxynol-9 preparations on vaginal flora and epithelium. Watts, D.H., Rabe, L., Krohn, M.A., Aura, J., Hillier, S.L. J. Infect. Dis. (1999)
- Applications of a microfabricated device for evaluating sperm function. Kricka, L.J., Nozaki, O., Heyner, S., Garside, W.T., Wilding, P. Clin. Chem. (1993)
- Barrier contraceptive use and HIV infection among high-risk women in Cameroon. Zekeng, L., Feldblum, P.J., Oliver, R.M., Kaptue, L. AIDS (1993)
- Sodium dodecyl sulfate and C31G as microbicidal alternatives to nonoxynol 9: comparative sensitivity of primary human vaginal keratinocytes. Krebs, F.C., Miller, S.R., Catalone, B.J., Welsh, P.A., Malamud, D., Howett, M.K., Wigdahl, B. Antimicrob. Agents Chemother. (2000)
- Novel thiourea compounds as dual-function microbicides. D'Cruz, O.J., Venkatachalam, T.K., Uckun, F.M. Biol. Reprod. (2000)
- Comparison of the action of nonoxynol-9 and chlorhexidine on sperm. Sharman, D., Chantler, E., Dukes, M., Hutchinson, F.G., Elstein, M. Fertil. Steril. (1986)
- Assessment of a new spermicidal agent against ejaculated dog and human spermatozoa in vitro. Vickery, B.H., Goodpasture, J.C., Bergstrom, K., Walker, K.A., Overstreet, J.W., Katz, D.F. Fertil. Steril. (1983)
- Preclinical assessment of the proinflammatory potential of microbicide candidates. Doncel, G.F., Chandra, N., Fichorova, R.N. J. Acquir. Immune Defic. Syndr. (2004)
- 'Chemical condoms' for the prevention of HIV infection: evaluation of novel agents against SHIV(89.6PD) in vitro and in vivo. Weber, J., Nunn, A., O'Connor, T., Jeffries, D., Kitchen, V., McCormack, S., Stott, J., Almond, N., Stone, A., Darbyshire, J. AIDS (2001)
- Effect of aryl 4-guanidinobenzoates on the acrosin activity of human spermatozoa. Kaminski, J.M., Smith, D., Reid, D.S., Kennedy, W., Jeyendran, R.S., Zaneveld, L.J. Biol. Reprod. (1987)
- Anti-human immunodeficiency virus type 1 microbicide cellulose acetate 1,2-benzenedicarboxylate in a human in vitro model of vaginal inflammation. Fichorova, R.N., Zhou, F., Ratnam, V., Atanassova, V., Jiang, S., Strick, N., Neurath, A.R. Antimicrob. Agents Chemother. (2005)
- Do spermicides containing nonoxynol-9 prevent sexually transmitted infections? A meta-analysis. Cook, R.L., Rosenberg, M.J. Sexually transmitted diseases. (1998)
- Rectal applications of nonoxynol-9 cause tissue disruption in a monkey model. Patton, D.L., Cosgrove Sweeney, Y.T., Rabe, L.K., Hillier, S.L. Sexually transmitted diseases. (2002)