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Chemical Compound Review

PubChem15330     1-methyl-4-(4- methylphenyl)sulfinyl-benzene

Synonyms: SureCN235851, T42803_ALDRICH, ACMC-209ecs, ANW-22874, NSC-73128, ...
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Disease relevance of NSC 73128


High impact information on NSC 73128

  • The enantiomeric purity of the (R)-methyl p-tolyl sulfoxide metabolite, generated by detergent-solubilized rabbit liver microsomes, decreased progressively with increasing substrate concentration, from a high of 96% enantiomeric excess at a substrate concentration of 5 microM to a low of 63% enantiomeric excess at a substrate concentration of 2 mM [2].


  1. Asymmetric reduction of racemic sulfoxides by dimethyl sulfoxide reductases from Rhodobacter capsulatus, Escherichia coli and Proteus species. Hanlon, S.P., Graham, D.L., Hogan, P.J., Holt, R.A., Reeve, C.D., Shaw, A.L., McEwan, A.G. Microbiology (Reading, Engl.) (1998) [Pubmed]
  2. Prochiral sulfoxidation as a probe for multiple forms of the microsomal flavin-containing monooxygenase: studies with rabbit FMO1, FMO2, FMO3, and FMO5 expressed in Escherichia coli. Rettie, A.E., Lawton, M.P., Sadeque, A.J., Meier, G.P., Philpot, R.M. Arch. Biochem. Biophys. (1994) [Pubmed]
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