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Chemical Compound Review

Oxyper     tetrasodium hydrogen peroxide dicarbonate

Synonyms: Perdox, AC1L4MFT, LS-51985, FT-0688134, W3396, ...
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Disease relevance of Oxyper


High impact information on Oxyper

  • METHODS: 50 adults were randomized to Crest Night Effects, a 19% sodium percarbonate gel that dries to form an adherent film, or a placebo gel without any peroxide source [2].
  • PURPOSE: To evaluate the hydrogen peroxide (HP) degradation kinetics of a 19% sodium percarbonate (5.3% HP released) direct application bleaching gel on the tooth surface and in saliva during use [3].
  • PURPOSE: To examine the effects of a paint-on 19% sodium percarbonate 'overnight' bleaching gel on the structure and integrity of enamel, dentin and some common restorative materials, with a laboratory cycling model [4].
  • METHODS: 57 adult volunteers were randomly assigned to Crest Night Effects, a 19% sodium percarbonate system packaged in unit dose sachets that when applied, dries to form an adherent film, or Colgate Simply White Night, a paint-on liquid in an applicator bottle at a concentration of 8.7% hydrogen peroxide [5].
  • Bleaching effect of sodium percarbonate on discolored pulpless teeth in vitro [1].


  1. Bleaching effect of sodium percarbonate on discolored pulpless teeth in vitro. Kaneko, J., Inoue, S., Kawakami, S., Sano, H. Journal of endodontics. (2000) [Pubmed]
  2. Placebo-controlled clinical trial of a 19% sodium percarbonate whitening film: initial and sustained whitening. Karpinia, K.A., Magnusson, I., Barker, M.L., Gerlach, R.W. American journal of dentistry. (2003) [Pubmed]
  3. Peroxide degradation kinetics of a direct application percarbonate bleaching film. Mahony, C., Barker, M.L., Engel, T.M., Walden, G.L. American journal of dentistry. (2003) [Pubmed]
  4. Impact of Crest Night Effects bleaching gel on dental enamel, dentin and key restorative materials. In vitro studies. White, D.J., Kozak, K.M., Zoladz, J.R., Duschner, H.J., Goetz, H. American journal of dentistry. (2003) [Pubmed]
  5. Randomized clinical trial comparing overnight use of two self-directed peroxide tooth whiteners. Gerlach, R.W., Barker, M.L. American journal of dentistry. (2003) [Pubmed]
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