Disease relevance of Potassium ferrate

• Treatment of Escherichia coli DNA polymerase-I with potassium ferrate (K2FeO4), a site-specific oxidizing agent for the phosphate group-binding sites of proteins, results in the irreversible inactivation of enzyme activity as judged by the loss of polymerization as well as 3'-5' exonuclease activity [1].
• Treatment of murine leukemia virus reverse transcriptase (MuLV RT) with potassium ferrate, an oxidizing agent known to oxidize amino acids involved in phosphate binding domains of proteins, results in the irreversible inactivation of both the DNA polymerase and the RNase H activities [2].
• Inactivation of coliphage Q beta by potassium ferrate [3].
• The kinetics of inactivation of a bacteriophage by potassium ferrate were studied with the F-specific RNA-coliphage Q beta [3].

High impact information on Potassium ferrate

• The characteristics of solid potassium ferrate were investigated and from XRD spectra it was found that samples of the solid have a tetrahedral structure with a space group of D(2h) (Pnma) and a=7.705A, b=5.863A, and c=10.36A [4].
• This result suggests that potassium ferrate is useful for decontamination of some waste water collections [5].

Analytical, diagnostic and therapeutic context of Potassium ferrate

• The obvious impact of cell architecture by potassium ferrate was found through scanning electron microscopy [6].

References