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Chemical Compound Review:

Iodide-131 iodide

Synonyms: iodine-131(1-), Iodide (131I-), AC1L4ZHY, 131I, 14914-30-8, ...

Robinson, G.A. et al., dell'Erba, L. et al., Kengen, R.A. et al.

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High impact information on iodide

For many years iodide-131 Hippuran has been used as a tracer to measure effective renal plasma flow (ERPF) [1].
Accumulations of tracer doses of iodide-125 or iodide-131 by the thyroid glands of these birds were approximately one-seventh (6-hour uptake) to one-thirtieth (18-hour uptake) as great as for control birds from non-disinfected areas [2].

Analytical, diagnostic and therapeutic context of iodide

We report the case of a hyperthyroid female patient whose 99mTcO4- scintigraphy showed two "hot" nodules, whereas Iodide-131 (131I-) revealed a lack of indicator uptake by the larger, and intense uptake by the smaller nodule [3].

References

Iodine-131 Hippuran for the estimation of renal plasma flow: requirements for radiochemical purity. Kengen, R.A., Meijer, S., van Zanten, A.K., Beekhuis, H., Kosterink, J.G., Albertus Piers, D. European journal of nuclear medicine. (1995) [Pubmed]
Accidental suppression of the accumulation of radioiodide by the thyroids of Japanese quail exposed to an iodinated disinfectant. Robinson, G.A., Elliott, N.C., Floto, F., Downie, S.E., Wasnidge, C. Poult. Sci. (1977) [Pubmed]
Association of hyperfunctioning thyroid adenoma with thyroid cancer presenting as "trapping only" nodule at 99mTcO4- scintigraphy. dell'Erba, L., Gerundini, P., Caputo, M., Bagnasco, M. J. Endocrinol. Invest. (2003) [Pubmed]

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