Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

AGN-PC-00IYBW 5-[4,5-dihydroxy-6- (hydroxymethyl)-3-(3,4...

Synonyms: AC1L4MPD, AR-1D7903, AC1Q5V6O, 115330-90-0, Kaikasaponin III

Choi, J. et al., Oh, S.R. et al., Lee, K.T. et al., Park, K.Y. et al.

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High impact information on Kaikasaponin III

The anticomplementary properties of kaikasaponin III (4) and soyasaponin I (8) from Pueraria lobata and their hydrolytic analogs were investigated in vitro [1].
Effect of kaikasaponin III obtained from Pueraria thunbergiana flowers on serum and hepatic lipid peroxides and tissue factor activity in the streptozotocin-induced diabetic rat [2].
We investigated the effect of kaikasaponin III (KS-III) on Phase I and II enzymes and tissue factor (TF) activity to elucidate the pharmacological actions of this immunosuppressive saponin in the diabetic rat [2].
Potent antimutagenic and their anti-lipid peroxidative effect of kaikasaponin III and tectorigenin from the flower of Pueraria thunbergiana [3].
We further found that tectorigenin and kaikasaponin III protected the Vero cell line (normal monkey kidney) from injury by hydrogen peroxide [4].

References

Effects of triterpenoids from Pueraria lobata on immunohemolysis: beta-D-glucuronic acid plays an active role in anticomplementary activity in vitro. Oh, S.R., Kinjo, J., Shii, Y., Ikeda, T., Nohara, T., Ahn, K.S., Kim, J.H., Lee, H.K. Planta Med. (2000) [Pubmed]
Effect of kaikasaponin III obtained from Pueraria thunbergiana flowers on serum and hepatic lipid peroxides and tissue factor activity in the streptozotocin-induced diabetic rat. Choi, J., Shin, M.H., Park, K.Y., Lee, K.T., Jung, H.J., Lee, M.S., Park, H.J. Journal of medicinal food. (2004) [Pubmed]
Potent antimutagenic and their anti-lipid peroxidative effect of kaikasaponin III and tectorigenin from the flower of Pueraria thunbergiana. Park, K.Y., Jung, G.O., Choi, J., Lee, K.T., Park, H.J. Arch. Pharm. Res. (2002) [Pubmed]
Hypoglycemic and hypolipidemic effects of tectorigenin and kaikasaponin III in the streptozotocin-lnduced diabetic rat and their antioxidant activity in vitro. Lee, K.T., Sohn, I.C., Kim, D.H., Choi, J.W., Kwon, S.H., Park, H.J. Arch. Pharm. Res. (2000) [Pubmed]

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