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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Vero Cells

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Disease relevance of Vero Cells


High impact information on Vero Cells


Chemical compound and disease context of Vero Cells


Biological context of Vero Cells


Anatomical context of Vero Cells


Associations of Vero Cells with chemical compounds

  • OFA from Vero cells binds to an Arg-Gly-Asp containing peptide (GRGDSPPK) isolating a heterodimer recognized by anti-OFA monoclonal antibodies, 13C2 and 23C6 [25].
  • In this study we demonstrate that EDIN induces a rapid morphological change in the Golgi structure of monkey kidney Vero cells that is similar to the changes elicited by brefeldin A (BFA) [26].
  • The similarities in the effects of EDIN and BFA in Vero cells also include the EDIN- or BFA-mediated protection of Vero cells from ricin cytotoxicity and prevention of the effects of EDIN or BFA on the distribution of Golgi markers by the pretreatment of Vero cells with guanosine 5'-[gamma-thio]triphosphate or forskolin [26].
  • The ability of ricin to intoxicate cells was much lower at 19 degrees C than at 37 degrees C and there was almost no sensitizing effect of cycloheximide and monensin at 19 degrees C. Studies by electron microscopy showed that ricin conjugated to horseradish peroxidase appeared in trans Golgi elements in Vero cells [5].
  • Tunicamycin, swainsonine, cycloheximide, and puromycin sensitized Vero cells and HeLa cells to abrin and ricin, as we have found previously with monensin (K. Sandvig and S. Olsnes, J. Biol. Chem., 257: 7504-7513, 1982) [5].

Gene context of Vero Cells


Analytical, diagnostic and therapeutic context of Vero Cells


  1. Altered chloride ion channel kinetics associated with the delta F508 cystic fibrosis mutation. Dalemans, W., Barbry, P., Champigny, G., Jallat, S., Dott, K., Dreyer, D., Crystal, R.G., Pavirani, A., Lecocq, J.P., Lazdunski, M. Nature (1991) [Pubmed]
  2. The mammalian G protein rhoC is ADP-ribosylated by Clostridium botulinum exoenzyme C3 and affects actin microfilaments in Vero cells. Chardin, P., Boquet, P., Madaule, P., Popoff, M.R., Rubin, E.J., Gill, D.M. EMBO J. (1989) [Pubmed]
  3. Herpes simplex virus DNA replication: the UL9 gene encodes an origin-binding protein. Olivo, P.D., Nelson, N.J., Challberg, M.D. Proc. Natl. Acad. Sci. U.S.A. (1988) [Pubmed]
  4. Increased sensitivity of SARS-coronavirus to a combination of human type I and type II interferons. Scagnolari, C., Vicenzi, E., Bellomi, F., Stillitano, M.G., Pinna, D., Poli, G., Clementi, M., Dianzani, F., Antonelli, G. Antivir. Ther. (Lond.) (2004) [Pubmed]
  5. Ability of inhibitors of glycosylation and protein synthesis to sensitize cells to abrin, ricin, Shigella toxin, and Pseudomonas toxin. Sandvig, K., Tønnessen, T.I., Olsnes, S. Cancer Res. (1986) [Pubmed]
  6. Nuclear protein migration involves two steps: rapid binding at the nuclear envelope followed by slower translocation through nuclear pores. Richardson, W.D., Mills, A.D., Dilworth, S.M., Laskey, R.A., Dingwall, C. Cell (1988) [Pubmed]
  7. Autoantibody to RNA polymerase I in scleroderma sera. Reimer, G., Rose, K.M., Scheer, U., Tan, E.M. J. Clin. Invest. (1987) [Pubmed]
  8. Shiga-like toxin-producing Escherichia coli in Seattle children: a prospective study. Bokete, T.N., O'Callahan, C.M., Clausen, C.R., Tang, N.M., Tran, N., Moseley, S.L., Fritsche, T.R., Tarr, P.I. Gastroenterology (1993) [Pubmed]
  9. gC1q-R/p32, a C1q-binding protein, is a receptor for the InlB invasion protein of Listeria monocytogenes. Braun, L., Ghebrehiwet, B., Cossart, P. EMBO J. (2000) [Pubmed]
  10. Molecular cloning and functional characterization of the receptor for Clostridium perfringens enterotoxin. Katahira, J., Inoue, N., Horiguchi, Y., Matsuda, M., Sugimoto, N. J. Cell Biol. (1997) [Pubmed]
  11. Characterization of hybrid molecules containing fragment A from diphtheria toxin linked to concanavalin A or the binding subunit of ricin toxin. Gilliland, D.G., Collier, R.J. J. Biol. Chem. (1981) [Pubmed]
  12. Metabolism and mode of action of (R)-9-(3,4-dihydroxybutyl)guanine in herpes simplex virus-infected vero cells. Stenberg, K., Larsson, A., Datema, R. J. Biol. Chem. (1986) [Pubmed]
  13. pH-dependent fusion of vesicular stomatitis virus with Vero cells. Measurement by dequenching of octadecyl rhodamine fluorescence. Blumenthal, R., Bali-Puri, A., Walter, A., Covell, D., Eidelman, O. J. Biol. Chem. (1987) [Pubmed]
  14. The host cell chaperone Hsp90 is essential for translocation of the binary Clostridium botulinum C2 toxin into the cytosol. Haug, G., Leemhuis, J., Tiemann, D., Meyer, D.K., Aktories, K., Barth, H. J. Biol. Chem. (2003) [Pubmed]
  15. Effect of acyclovir on the deoxyribonucleoside triphosphate pool levels in Vero cells infected with herpes simplex virus type 1. Furman, P.A., Lambe, C.U., Nelson, D.J. Am. J. Med. (1982) [Pubmed]
  16. Microtubules containing detyrosinated tubulin are less dynamic. Kreis, T.E. EMBO J. (1987) [Pubmed]
  17. Hypersensitivity to diphtheria toxin by mouse cells expressing both diphtheria toxin receptor and CD9 antigen. Brown, J.G., Almond, B.D., Naglich, J.G., Eidels, L. Proc. Natl. Acad. Sci. U.S.A. (1993) [Pubmed]
  18. Expression of functional diphtheria toxin receptors on highly toxin-sensitive mouse cells that specifically bind radioiodinated toxin. Naglich, J.G., Rolf, J.M., Eidels, L. Proc. Natl. Acad. Sci. U.S.A. (1992) [Pubmed]
  19. Long-term agonist exposure induces upregulation of beta 3-adrenergic receptor expression via multiple cAMP response elements. Thomas, R.F., Holt, B.D., Schwinn, D.A., Liggett, S.B. Proc. Natl. Acad. Sci. U.S.A. (1992) [Pubmed]
  20. Selective inhibition of sodium-linked and sodium-independent bicarbonate/chloride antiport in Vero cells. Madshus, I.H., Olsnes, S. J. Biol. Chem. (1987) [Pubmed]
  21. Transport of an external Lys-Asp-Glu-Leu (KDEL) protein from the plasma membrane to the endoplasmic reticulum: studies with cholera toxin in Vero cells. Majoul, I.V., Bastiaens, P.I., Söling, H.D. J. Cell Biol. (1996) [Pubmed]
  22. Selective destruction of nerve growth factor receptor-bearing cells in vitro using a hybrid toxin composed of ricin A chain and a monoclonal antibody against the nerve growth factor receptor. DiStefano, P.S., Schweitzer, J.B., Taniuchi, M., Johnson, E.M. J. Cell Biol. (1985) [Pubmed]
  23. Comparative biochemical and immunocytochemical studies reveal differences in the effects of Clostridium perfringens enterotoxin on polarized CaCo-2 cells versus Vero cells. Singh, U., Mitic, L.L., Wieckowski, E.U., Anderson, J.M., McClane, B.A. J. Biol. Chem. (2001) [Pubmed]
  24. Localization of O-glycan initiation, sphingomyelin synthesis, and glucosylceramide synthesis in Vero cells with respect to the endoplasmic reticulum-Golgi intermediate compartment. Schweizer, A., Clausen, H., van Meer, G., Hauri, H.P. J. Biol. Chem. (1994) [Pubmed]
  25. The osteoclast functional antigen, implicated in the regulation of bone resorption, is biochemically related to the vitronectin receptor. Davies, J., Warwick, J., Totty, N., Philp, R., Helfrich, M., Horton, M. J. Cell Biol. (1989) [Pubmed]
  26. Bacterial ADP-ribosyltransferase with a substrate specificity of the rho protein disassembles the Golgi apparatus in Vero cells and mimics the action of brefeldin A. Sugai, M., Chen, C.H., Wu, H.C. Proc. Natl. Acad. Sci. U.S.A. (1992) [Pubmed]
  27. Membrane-anchored heparin-binding EGF-like growth factor (HB-EGF) and diphtheria toxin receptor-associated protein (DRAP27)/CD9 form a complex with integrin alpha 3 beta 1 at cell-cell contact sites. Nakamura, K., Iwamoto, R., Mekada, E. J. Cell Biol. (1995) [Pubmed]
  28. Combinatorial association and abundance of components of interferon-stimulated gene factor 3 dictate the selectivity of interferon responses. Bluyssen, H.A., Muzaffar, R., Vlieststra, R.J., van der Made, A.C., Leung, S., Stark, G.R., Kerr, I.M., Trapman, J., Levy, D.E. Proc. Natl. Acad. Sci. U.S.A. (1995) [Pubmed]
  29. Human heat shock factor 1 is predominantly a nuclear protein before and after heat stress. Mercier, P.A., Winegarden, N.A., Westwood, J.T. J. Cell. Sci. (1999) [Pubmed]
  30. Inhibition of different Lassa virus strains by alpha and gamma interferons and comparison with a less pathogenic arenavirus. Asper, M., Sternsdorf, T., Hass, M., Drosten, C., Rhode, A., Schmitz, H., Günther, S. J. Virol. (2004) [Pubmed]
  31. Efficiency of measles virus entry and dissemination through different receptors. Schneider, U., von Messling, V., Devaux, P., Cattaneo, R. J. Virol. (2002) [Pubmed]
  32. Characterization and immunolocalization of bovine N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase. Mullis, K.G., Kornfeld, R.H. J. Biol. Chem. (1994) [Pubmed]
  33. Activation and antiviral effect of acyclovir in cells infected with a varicella-like simian virus. Fyfe, J.A., Biron, K.K., McKee, S.A., Kelly, C.M., Elion, G.B., Soike, K.F. Am. J. Med. (1982) [Pubmed]
  34. Antibodies against synthetic peptides of herpes simplex virus type 1 glycoprotein D and their capability to neutralize viral infectivity in vitro. Weijer, W.J., Drijfhout, J.W., Geerligs, H.J., Bloemhoff, W., Feijlbrief, M., Bos, C.A., Hoogerhout, P., Kerling, K.E., Popken-Boer, T., Slopsema, K. J. Virol. (1988) [Pubmed]
  35. Enhancement and suppression by actinomycin D of a Vero cell nontransmissible measles infection. Winston, S.H., Rustigian, R. Infect. Immun. (1979) [Pubmed]
  36. Isolation, cultivation, and partial characterization of the ELB agent associated with cat fleas. Radulovic, S., Higgins, J.A., Jaworski, D.C., Dasch, G.A., Azad, A.F. Infect. Immun. (1995) [Pubmed]
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