Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Chemical Compound Review:

AGN-PC-00IO46 N-[3-[3- (diaminomethylideneamino) propyl]-5...

Synonyms: KST-1B1589, AC1Q5NVT, AR-1B1315, AC1L4YR7, 17297-77-7, ...

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on oxyluciferin

The firefly bioluminescence reaction, which uses luciferin, Mg-ATP, and molecular oxygen to yield an electronically excited oxyluciferin, is carried out by luciferase and visible light is emitted [1].
The original mechanism of bioluminescence color determination advanced by White and co-workers was based on the concept that the keto and enol tautomers of the emitter oxyluciferin produce red and green light, respectively [2].
Mutagenesis and modelling studies suggest that several invariant residues in the putative luciferin-binding site of PxRE luciferase cannot interact with excited oxyluciferin [3].

Associations of oxyluciferin with other chemical compounds

The activity regenerating luciferin from the luminescent product oxyluciferin was found in the protein fraction of a lantern extract from Photinus pyralis [4].

References

The influence of insertion of a critical residue (arg356) in structure and bioluminescence spectra of firefly luciferase. Tafreshi, N.K.h., Hosseinkhani, S., Sadeghizadeh, M., Sadeghi, M., Ranjbar, B., Naderi-Manesh, H. J. Biol. Chem. (2007) [Pubmed]
Yellow-green and red firefly bioluminescence from 5,5-dimethyloxyluciferin. Branchini, B.R., Murtiashaw, M.H., Magyar, R.A., Portier, N.C., Ruggiero, M.C., Stroh, J.G. J. Am. Chem. Soc. (2002) [Pubmed]
Active-site properties of phrixotrix railroad worm green and red bioluminescence-eliciting luciferases. Viviani, V.R., Arnoldi, F.G., Venkatesh, B., Neto, A.J., Ogawa, F.G., Oehlmeyer, A.T., Ohmiya, Y. J. Biochem. (2006) [Pubmed]
Oxyluciferin, a luminescence product of firefly luciferase, is enzymatically regenerated into luciferin. Gomi, K., Kajiyama, N. J. Biol. Chem. (2001) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

Editor

Share