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Chemical Compound Review

Lefetamine     N,N-dimethyl-1,2-diphenyl- ethanamine

Synonyms: CHEMBL2106355, SureCN1650099, NSC-31924, NSC31924, LS-68099, ...
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Disease relevance of Lefetamine


Psychiatry related information on Lefetamine


High impact information on Lefetamine

  • Dual effects of lephetamine on spontaneous and evoked neuronal firing in the somatosensory cortex of the rat [3].
  • Furthermore, experimental results showed that lefetamine induced a naloxone-reversible inhibition of the guinea-pig ileum contractile response to electric field stimulation, and that naloxone pretreatment of mice prevented lefetamine antinociceptive activity in the hot-plate test [4].


  1. Opioid activity of lefetamine. De Montis, M.G., Devoto, P., Bucarelli, A., Tagliamonte, A. Pharmacological research communications. (1985) [Pubmed]
  2. Lefetamine: new abuse of an old drug--clinical evaluation of opioid activity. Mannelli, P., Janiri, L., De Marinis, M., Tempesta, E. Drug and alcohol dependence. (1989) [Pubmed]
  3. Dual effects of lephetamine on spontaneous and evoked neuronal firing in the somatosensory cortex of the rat. Janiri, L., Persico, A.M., Tempesta, E. Neuropharmacology (1989) [Pubmed]
  4. Clinical and experimental evidence of an opiate-like activity of lefetamine. Paroli, E., Nencini, P., Moscucci, M. Pharmacological research communications. (1984) [Pubmed]
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