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Chemical Compound Review:

INDORAMIN N-[1-[2-(1H-indol-3- yl)ethyl]-4...

Synonyms: Indoramina, Indoramine, Indoraminum, SureCN49517, SureCN49518, ...

Müller-Schweinitzer, E., Morrow, A.L. et al.

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High impact information on INDORAMIN

Prazosin, indoramine, and dihydroergocryptine competitions with [3H]prazosin are steep and monophasic, and model best to a single binding site [1].
The use of the antagonists phentolamine, indoramine, pimozide, pizotifen, and methysergide provided evidence that ergometrine and 5-HT induce contraction of coronary arteries by stimulating the same type of 5-HT receptor, which, however, seems to be different from the 5-HT receptor present in basilar arteries [2].

References

Characterization of alpha 1-adrenergic receptor subtypes in rat brain: a reevaluation of [3H]WB4104 and [3H]prazosin binding. Morrow, A.L., Creese, I. Mol. Pharmacol. (1986) [Pubmed]
The mechanism of ergometrine-induced coronary arterial spasm: in vitro studies on canine arteries. Müller-Schweinitzer, E. J. Cardiovasc. Pharmacol. (1980) [Pubmed]

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