Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

AC1MW3T2 3-methylindole

Synonyms: 3-methyl-1H-indolium, 3-methyl-1H-indol-1-ium

This record was replaced with 6736.

Bray, T.M. et al., Bray, T.M. et al.

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High impact information on Skatole

The organ specificity in binding suggests that covalent binding by lung microsomes may be related to the mechanism of 3MI-induced lung injury [1].
The accumulation of radioactivity in lung microsomes may be related to the metabolism of 3MI [2].
The tissue and subcellular distribution and urinary excretion pattern of radioactivity in rabbits after intratracheal administration of a 14C-labeled pulmonary toxin, 3-methylindole (3MI), was studied [2].

References

In vitro covalent binding of 3-[14C]methylindole metabolites in goat tissues. Bray, T.M., Carlson, J.R., Nocerini, M.R. Proc. Soc. Exp. Biol. Med. (1984) [Pubmed]
Tissue and subcellular distribution and excretion of 3-[14C]methylindole in rabbits after intratracheal infusion. Bray, T.M., Carlson, J.R. Can. J. Physiol. Pharmacol. (1980) [Pubmed]

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