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Chemical Compound Review

CHEMBL22531     3-phenoxybenzaldehyde

Synonyms: ACMC-1CTWT, AG-F-39673, ANW-29112, AC1Q6PSU, ACT06996, ...
 
 
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High impact information on BRN 0511662

  • From a consideration of the dimensions of 3-phenoxybenzaldehyde, which was a relatively good substrate, the mALDH possesses a narrow cleft within the active site that is at least 7.5 angstroms wide and extends at least 12 angstroms from the catalytic residue (probably cysteine) [1].
 

Analytical, diagnostic and therapeutic context of BRN 0511662

  • A procedure involving an extraction step and further gas chromatographic analysis with flame ionization detection to determine residues of acrinathrine and its main metabolite, 3-phenoxybenzaldehyde, in honey is proposed [2].

References

  1. Rat hepatic microsomal aldehyde dehydrogenase. Identification of 3- and 4-substituted aromatic aldehydes as substrates of the enzyme. Martini, R., Murray, M. Chem. Res. Toxicol. (1996) [Pubmed]
  2. Gas chromatographic determination of acrinathrine and 3-phenoxybenzaldehyde residues in honey. Bernal, J.L., Jiménez, J.J., del Nozal, M.J., Higes, M., Llorente, J. Journal of chromatography. A. (2000) [Pubmed]
 
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