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Chemical Compound Review:

Tisercin 3-(2-methoxyphenothiazin-10- yl)-N,N,2...

Synonyms: Hirnamin, Neurocil, Nozinane, Veractil, Tizercine, ...

Törnebrandt, K. et al., Ishikawa, T. et al., Hese, R.T.

Ishikawa, Zhu, Maeda,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of METHOTRIMEPRAZINE

Cardiac arrest in a young woman treated with amitriptyline combined with levopromazine [1].
Modified neurolept anaesthesia without levopromazine pretreatment combined with careful monitoring seems to be a safe procedure for carcinoid patients [2].

High impact information on METHOTRIMEPRAZINE

In the patients treated with levopromazine, however, significant changes were observed in heart rate, mean pulmonary artery pressure, cardiac index, and left and right ventricular stroke work especially during flushing episodes [2].
Cardiac muscle cells showed the strongest respiratory inhibition by Serenace and were least inhibited by Hirnamin [3].

Analytical, diagnostic and therapeutic context of METHOTRIMEPRAZINE

The premedication in five patients was supplemented with levopromazine [2].

References

Cardiac arrest in a young woman treated with amitriptyline combined with levopromazine. Hese, R.T. The British journal of psychiatry : the journal of mental science. (1982) [Pubmed]
Circulation, respiration and serotonin levels in carcinoid patients during neurolept anaesthesia. Törnebrandt, K., Nobin, A., Ericsson, M., Thomson, D. Anaesthesia. (1983) [Pubmed]
Effects of therapeutic agents on cellular respiration as an indication of metabolic activity. Ishikawa, T., Zhu, B.L., Maeda, H. Human & experimental toxicology. (2006) [Pubmed]

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