Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Mepihexal N-(2,6-dimethylphenyl)-1- methyl-piperidine...

Synonyms: Carbocain, Polocaine, Carbocaine, Scandicain, Scandicane, ...

Malorny, U. et al., Schomäcker, K. et al.

Schomäcker, Dietlein, Mödder, Boddenberg-Pätzold, Zimmermanns, Fischer, Schicha,

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High impact information on mepivacaine

The addition of Scandicain did not produce low-molecular 90Y or 169Er in the presence of synovial fluid [1].
Scandicain, proteinase K, and pronase treatment was mitogenic to macrophages in contrast to mechanical detachment [2].
After mechanical detachment of macrophages or pretreatment with scandicain, adherence to plastic, latex phagocytosis and chemotaxis was not or only slightly impaired, whereas the same functions after protease treatment were greatly reduced or even abolished and were only recovered after another culture period [2].

References

Stability of radioactive colloids for radiation synovectomy: influence of X-ray contrast agents, anaesthetics and glucocorticoids in vitro. Schomäcker, K., Dietlein, M., Mödder, G., Boddenberg-Pätzold, B., Zimmermanns, B., Fischer, T., Schicha, H. Nuclear medicine communications. (2005) [Pubmed]
Influence of various detachment procedures on the functional state of cultured murine macrophages. Malorny, U., Neumann, C., Sorg, C. Immunobiology (1981) [Pubmed]

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